NCT03665064

Brief Summary

To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.

Trial Health

83
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for all trials

Timeline
8mo left

Started Jan 2000

Longer than P75 for all trials

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress98%
Jan 2000Dec 2026

Study Start

First participant enrolled

January 1, 2000

Completed
18.7 years until next milestone

First Submitted

Initial submission to the registry

September 7, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 11, 2018

Completed
8.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

March 16, 2026

Status Verified

March 1, 2026

Enrollment Period

27 years

First QC Date

September 7, 2018

Last Update Submit

March 12, 2026

Conditions

Pituitary DiseasesPituitary Neoplasms

Keywords

Pituitary tumorAcromegalyCushingProlactinoma

Outcome Measures

Primary Outcomes (1)

  • Progression free survival after pituitary surgery

    Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence

    up to 17 years post surgery

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

tertiary referral center

You may qualify if:

  • patients with confirmed pituitary disease

You may not qualify if:

  • patients who do not have confirmed pituitary disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Pituitary DiseasesPituitary NeoplasmsAcromegalyProlactinoma

Condition Hierarchy (Ancestors)

Hypothalamic DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesEndocrine System DiseasesEndocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHypothalamic NeoplasmsSupratentorial NeoplasmsBrain NeoplasmsCentral Nervous System NeoplasmsNervous System NeoplasmsBone Diseases, EndocrineBone DiseasesMusculoskeletal DiseasesHyperpituitarismAdenomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic Type

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2018

First Posted

September 11, 2018

Study Start

January 1, 2000

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

March 16, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share