Measurement of Tricuspid AnnularPlane Systolic Excursion in Transesophageal Echocardiography

NCT03649854 | Completed

• 1 other identifier: 2014/00576
• Study Type: observational
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to measure TAPSE in TEE using two deep transgastric views. This is a prospective comparative diagnostic study where 21 CABG patients who are enrolled for the study will be studied during the intraoperative period. The choice of general anaesthesia, hemodynamic management will be at the discretion of the anaesthesiologist in charge of the patient. The monitoring technique is standard as per any cardiac surgery with cardiopulmonary bypass. After induction of anaesthesia, TEE probe will be inserted by the PI or the Co-Investigator and the required TEE standard views and deep TG view of the right heart at zero degree and Deep TG view at 100-150 degrees will be acquired TAPSE will be measured in both the views using Mmode. The measurement will be done as follows: After acquiring the deep TG views the M mode cursor is aligned with the longitudinal motion the lateral tricuspid annulus. Once the Mmode picks up a good signal, 3 cycles are chosen and measured using calipers, and an average reading is taken. TAPSE will be used to evaluate the right heart function during the intraoperative period so that the patients with deteriorating right heart function can be identified and treatment started early. The potential benefits include the simplicity and reproducibility of the technique.

Conditions

Right Heart Dysfunction

Keywords

TAPSE; Right heart function

Outcome Measures

Primary Outcomes (1)

• New method for assessing right heart function

  TAPSE mesurement using M mode in the deep transgastric right heart view at zero degrees

  During systole intraoperatively

Eligibility Criteria

• Age: 21 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients scheduled for coronary artery bypass surgery at National university hospital are included in the study

You may qualify if:

• Ejection fraction greater than 40% No other valvular involvement other than mild mitral regurgitation

You may not qualify if:

• Hemodynamically unstable patients
• Intubated and sedated patients
• Emergency patients from cath lab

Sponsors & Collaborators

• National University Hospital, Singapore: lead

Study Sites (1)

National university Hospital

Singapore, 119074, Singapore

Location

Study Officials

• Lalitha Manickam

  NUH

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 23, 2018
• First Posted: August 28, 2018
• Study Start: August 15, 2014
• Primary Completion: March 23, 2015
• Study Completion: August 14, 2015
• Last Updated: August 28, 2018

Record last verified: 2018-08

Locations

SG (1)