PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress

NCT03647397 | Completed

• 1 other identifier: Molekule-08082018
• Study Type: interventional
• Target: 274
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress. The study will take place at Mercyhealth Hospital - Rockton Avenue where all 23 pediatric rooms will be outfitted with portable PECO air purifying units. The main outcomes are the length of stay and progression to ICU, which will be compared with historical controls.

Conditions

Asthma; Pneumonia; Respiratory Distress Syndrome

Keywords

asthma; environmental intervention; respiratory distress; pediatric hospitalization; pneumonia; bronchiolitis

Outcome Measures

Primary Outcomes (1)

• Length of stay

  Total length of hospital stay for patient

  5 months

Secondary Outcomes (1)

• Readmission rate

  1 months

Study Arms (1)

PECO

EXPERIMENTAL

All pediatric patients admitted for respiratory distress will have the intervention of Photo Electrochemical Oxidation (PECO) for Air Purification.

Device: Photo Electrochemical Oxidation (PECO) for Air Purification

Interventions

Photo Electrochemical Oxidation (PECO) for Air Purification DEVICE

PECO air purifiers from Molekule will be placed in every patient room. Health metrics will be tracked for patients whose diagnosis is respiratory distress.

PECO

Eligibility Criteria

• Age: 1 Year - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• J00-J06: Acute upper respiratory infections
• J09-J18: Influenza and pneumonia
• J20-J22: Other acute lower respiratory infections
• J30-J39: Other diseases of upper respiratory tract
• J40-J47: Chronic lower respiratory diseases
• J60-J70: Lung diseases due to external agents
• J80-J84: Other respiratory diseases principally affecting the interstitium
• J85-J86: Suppurative and necrotic conditions of the lower respiratory tract
• J90-J94: Other diseases of the pleura
• J95-J95: Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

You may not qualify if:

• Any patient admitted to the NICU
• Patients in the ER only
• Any patient with non-respiratory conditions
• Adults

Sponsors & Collaborators

• Molekule: lead
• Mercy Health System: collaborator

Study Sites (1)

Mercyhealth Hospital - Rockton Avenue

Rockford, Illinois, 61103, United States

Location

MeSH Terms

Conditions

Asthma; Pneumonia; Respiratory Distress Syndrome; Dyspnea; Bronchiolitis

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Respiratory Tract Infections; Infections; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Bronchitis

Study Officials

• Nikhil Rao

  Molekule

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 20, 2018
• First Posted: August 27, 2018
• Study Start: August 8, 2018
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2018
• Last Updated: May 17, 2019

Record last verified: 2019-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)