Rhythmic Entrainment in Bilingual Speakers With Dysarthria

NCT03645265 | Terminated

• 1 other identifier: 2017-0851
• Study Type: interventional
• Target: 6
• Locations: 1 country
• Sites: 1

Brief Summary

The objectives of this study are to determine i) the effect of rhythmic entrainment of speech with hand gestures and auditory rhythmic cues on intelligibility and speech naturalness in Spanish-accented speakers of English in two pathology groups: ataxic dysarthria and hypokinetic dysarthria secondary to idiopathic Parkinson's disease; and ii) the extent to which speech rate and effort are control parameters of entrainment. These objectives will be achieved with the following specific aims: Specific Aim 1: Determine the effect of three rates of hand gestures and auditory rhythmic cues and the degree to which learning and carry-over occur. Specific Aim 2: Determine the effect of increased speech effort, operationalized as clear speech, and the interaction effect of clear speech with hand gestures and auditory rhythmic cues. Specific Aim 3: Investigate the perception of speech rhythm and its relationship to entrainment.

Conditions

Parkinson Disease; Ataxia

Keywords

speech rhythm; speech therapy

Outcome Measures

Primary Outcomes (1)

• Intelligibility

  Intelligibility = the accuracy with which a listener understands a speaker. It will be measured by having the subjects undergoing the therapy ("the talkers") read 28 phrases using accompanying gesture or auditory cues and listeners will transcribe the sentences. The number of words accurately transcribed / the number of words in the phrase = intelligibility score for each phrase per listener

  immediately upon completion of the therapy

Secondary Outcomes (2)

• Ease of understanding

  Immediately upon completion of the therapy

• Speech naturalness

  immediately upon completion of the therapy

Study Arms (2)

Gestures

EXPERIMENTAL

Use of hand gestures to improve speech rhythm and speech production

Behavioral: Gestures

Auditory

EXPERIMENTAL

Use of auditory cues to improve speech rhythm and speech production

Behavioral: Auditory

Interventions

Auditory BEHAVIORAL

Use of auditory cues to improve speech production

Auditory

Gestures BEHAVIORAL

Use of gestures to improve speech production

Gestures

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• diagnosis of idiopathic Parkinson's disease (4) or dysarthria secondary to ataxia (4) or healthy (4)
• monolingual speaker of American English (6) or native speaker of Spanish who speaks English with a Spanish accent (6)
• age 21 or older

You may not qualify if:

• Cognitive impairment that prevents participation in the therapy
• Fluent speakers of languages other than English or Spanish
• younger than 21 years

Sponsors & Collaborators

• Herbert H. Lehman College, City University of New York: lead
• University of Utah: collaborator

Study Sites (1)

Lehman College

The Bronx, New York, 10468, United States

Location

MeSH Terms

Conditions

Parkinson Disease; Ataxia; Communication Disorders

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Dyskinesias; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurobehavioral Manifestations; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Alison Behrman, PhD

  Lehman College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Single case experimental design

Study Record Dates

• First Submitted: August 21, 2018
• First Posted: August 24, 2018
• Study Start: September 1, 2018
• Primary Completion: February 20, 2019
• Study Completion: February 20, 2019
• Last Updated: February 26, 2019

Record last verified: 2019-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR
• Time Frame: After completion of the study and publication of the data
• Access Criteria: Researchers who have contacted me directly with clear purpose and plan for use of data and then have IRB approval.

Locations

US (1)