NCT03643809

Brief Summary

Systemic autoinflammatory diseases (SAIDs) are inflammatory conditions caused by a defect of the innate immune system. Most are hereditary, but little is known on recent entities. The investigators aim to (1) establish correlations between the main mutations and symptoms presented by patients (genotype-phenotype correlation), and (2) describe the most recently described clinical, genetic, and demographic characteristics of SAIDs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 7, 2018

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

July 26, 2018

Completed
28 days until next milestone

First Posted

Study publicly available on registry

August 23, 2018

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2019

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2020

Completed
Last Updated

March 10, 2020

Status Verified

March 1, 2020

Enrollment Period

7 months

First QC Date

July 26, 2018

Last Update Submit

March 9, 2020

Conditions

Autoinflammatory Diseases

Keywords

Systemic autoinflammatory diseases (SAIDs)

Outcome Measures

Primary Outcomes (1)

  • Number of genetically ascertained patients

    Number of genetically ascertained patients

    1 day

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients referred to the laboratory for suspected systemic autoinflammatory diseases (SAID)

You may qualify if:

  • \- NGS autoinflammatory panel performed

You may not qualify if:

  • \- None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Uh Montpellier

Montpellier, Montepllier, 34295, France

Location

Study Officials

  • Guillaume SARRABAY

    UH MONTPELLIER

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 26, 2018

First Posted

August 23, 2018

Study Start

July 7, 2018

Primary Completion

January 30, 2019

Study Completion

January 30, 2020

Last Updated

March 10, 2020

Record last verified: 2020-03

Locations

FR(1)