NCT03643718

Brief Summary

The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a worldwide register of traumatic and non traumatic surgical emergencies. This will give the opportunity to evaluate results on a macro-data basis and to give index allowing stratifying, evaluating and improving the outcomes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
53mo left

Started Jul 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress58%
Jul 2020Sep 2030

First Submitted

Initial submission to the registry

May 14, 2018

Completed
3 months until next milestone

First Posted

Study publicly available on registry

August 23, 2018

Completed
1.9 years until next milestone

Study Start

First participant enrolled

July 1, 2020

Completed
10.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2030

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2030

Last Updated

July 14, 2020

Status Verified

July 1, 2020

Enrollment Period

10.2 years

First QC Date

May 14, 2018

Last Update Submit

July 10, 2020

Conditions

Acute AppendicitisAcute CholecystitisAcute DiverticulitisPost-operative ComplicationsAcute PancreatitisPerforated Gastro-duodenal UlcersAdhesive Small Bowell OcclusionColonic Neoplastic EmergenciesGynecological EmergenciesVascular EmergenciesIntestinal IschemiaAbdominal Wall HerniaForeign BodiesCaustic IngestionTrauma

Outcome Measures

Primary Outcomes (2)

  • Rate of patients treated with surgery

    Evaluate the rate of operative treatment for each different disease according to the different enviroment; for each intervention the surgical approach (laparotomic, mini-invasive, laparoscopic) will be evaluated.

    Until hospital discharge, approximately 2 weeks

  • Rate of patients treated with conservative treatment

    Evaluate the conservative treatment rate for each different disease according to patient's characteristics and the enviroinment.

    Until hospital discharge, approximately 2 weeks

Secondary Outcomes (2)

  • Mortality

    Until hospital discharge, approximately 2 weeks

  • Morbidity

    Until hospital discharge, approximately 2 weeks

Interventions

Emergency General SurgeryPROCEDURE

Emergency General Surgery and Trauma operative/non operative management

Also known as: Trauma

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients affected by an acute surgical disease and/or who may require to be undergone to the emergency surgeon attention to be managed either with an operative or a non-operative approach.

You may qualify if:

  • Patients affected by an acute surgical disease
  • Patients with indication to be referred to the emergency surgeon attention
  • Patients to be operated or to be treated with non-operative approach without surgical intervention

You may not qualify if:

  • Patients not affected by an acute surgical disease
  • Patients without indication to be referred to the emergency surgeon attention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

General, Emergency and Trauma surgery, University Hospital of Pisa

Pisa, Italy

RECRUITING

Related Publications (1)

  • Coccolini F, Mazzoni A, Cremonini C, Cobuccio L, Pucciarelli M, Vetere G, Borelli B, Strambi S, Musetti S, Miccoli M, Cremolini C; WIRES-T Study Group; Tartaglia D, Chiarugi M. Colorectal neoplastic emergencies in immunocompromised patients: preliminary result from the Web-based International Register of Emergency Surgery and Trauma (WIRES-T trial). Updates Surg. 2023 Sep;75(6):1579-1587. doi: 10.1007/s13304-023-01521-8. Epub 2023 May 9.

    PMID: 37160552DERIVED

MeSH Terms

Conditions

AppendicitisCholecystitis, AcutePancreatitisHernia, AbdominalForeign BodiesWounds and Injuries

Condition Hierarchy (Ancestors)

Intraabdominal InfectionsInfectionsGastroenteritisGastrointestinal DiseasesDigestive System DiseasesCecal DiseasesIntestinal DiseasesCholecystitisGallbladder DiseasesBiliary Tract DiseasesPancreatic DiseasesHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Central Study Contacts

Federico Coccolini, MD

CONTACT

0039-050996123federico.coccolini@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Weeks
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Surgeon

Study Record Dates

First Submitted

May 14, 2018

First Posted

August 23, 2018

Study Start

July 1, 2020

Primary Completion (Estimated)

September 1, 2030

Study Completion (Estimated)

September 1, 2030

Last Updated

July 14, 2020

Record last verified: 2020-07

Locations

IT(1)