Cognitive Dysfunction in Patients With Cancer Pain

NCT03641820 | Unknown

• 1 other identifier: FJZL20180407
• Study Type: observational
• Target: 928
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the occurrence of cognitive dysfunction in cancer patients with pain in China.Analysis of patients with different cancer pain, different analgesic drugs and different treatments are associated with the severity of cognitive dysfunction, to provide relevant evidence for the next screening, prediction, prevention and treatment. In order to achieve the purpose of improving the quality of life of cancer patients.

Conditions

Cognitive Dysfunction

Outcome Measures

Primary Outcomes (1)

• Prevalence of Cancer-related cognitive dysfunction patient with pain

  Statistical analysis was performed SPSS 21.0. The t test was used for comparison between groups, and the X2 test was used for the count data. The logistic regression model was used for multivariate analysis. The regression coefficient, P value and OR value were calculated by age, ethnicity, education level, treatment plan and income as covariates.

  6 months

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Malignant tumor patient with pain

You may qualify if:

• Malignant tumor patient with pain are confirmed by histopathology or cytology (NRS score ≥ 1);
• Understand Chinese through verbal and written communication, read and write Chinese, numbers, and complete questionnaire surveys;
• Male or female, age 18-75 years old;
• ECOG 0-2, expected to survive for more than 3 months;
• no obvious dysfunction of heart, lung, liver, kidney, blood system (≤I degree);
• patients voluntarily sign informed consent

You may not qualify if:

• Pregnant women and lactating women.
• Also participate in clinical trials of drugs that have not been approved for marketing.
• Patients with depression (evaluated by the Hamilton Depression Scale).
• Active bleeding or bleeding tendency.
• Serious or uncontrolled medical conditions and infected people.
• Patients with structural heart disease, such as coronary heart disease, unstable angina, especially patients with congestive heart failure and atrial fibrillation, atrial flutter history, and patients with hypertension, hypercoagulable state and severe cerebrovascular disease.
• History of thromboembolic disease; long-term oral administration of aspirin and other anticoagulants.
• Preventive Whole Brain Irradiation (PCI).
• Bone marrow invasion or bone marrow metastasis.
• Patients with severe or uncontrollable mental illness.

Sponsors & Collaborators

• Fujian Cancer Hospital: lead

Study Sites (1)

Department of Nursing, Fujian Provincial Cancer Hospital

Fuzhou, Fujian, 350014, China

RECRUITING

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Central Study Contacts

huiyu luo

CONTACT

13799365820; 13799365820@163.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 6 Months
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 20, 2018
• First Posted: August 22, 2018
• Study Start: August 21, 2018
• Primary Completion: February 28, 2019
• Study Completion: February 28, 2019
• Last Updated: August 22, 2018

Record last verified: 2018-08

Locations

CN (1)