NCT03639012

Brief Summary

Randomised control trial of 150 paediatric patients aged between 3-8years. One group will receive a preoperative carbohydrate oral drink and the other group will receive current standard care (no drink) prior to undergoing tonsillectomy and/or adenoidectomy. Outcomes to be reported will be: 1) patient and parent satisfaction; 2) post operative pain score at: recover, 1 hour post op, prior to discharge home and then day 1 postoperatively; 3) PONV rates in recovery, prior to discharge home and again on Day 1 postoperatively; 4) sleep quality night after surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable postoperative-pain

Timeline
Completed

Started Sep 2018

Typical duration for not_applicable postoperative-pain

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 11, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 20, 2018

Completed
12 days until next milestone

Study Start

First participant enrolled

September 1, 2018

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

August 21, 2018

Status Verified

August 1, 2018

Enrollment Period

1.4 years

First QC Date

July 11, 2018

Last Update Submit

August 20, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postoperative Pain Score

    Visual analogue scale (0-5)

    day 1 postoperatively

Secondary Outcomes (3)

  • Patient and parent satisfaction

    Day 1 postoperatively

  • Quality of sleep

    Day 1 post operative

  • Postoperative Nausea and Vomiting

    4 hours postoperatively

Study Arms (2)

Carbohydrate loading

ACTIVE COMPARATOR

Patients to receive an oral preoperative carbohydrate drink

Dietary Supplement: Carbohydrate drink

No Carbohydrate loading

NO INTERVENTION

Current standard of care

Interventions

Carbohydrate drinkDIETARY_SUPPLEMENT

Children randomised to this group will receive a preoperative carbohydrate drink 90-120mins prior to surgery

Carbohydrate loading

Eligibility Criteria

Age3 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Undergoing Tonsillectomy and/or adenoidectomy
  • consented to undertake preop carbohydrate drink and follow up procedures

You may not qualify if:

  • Increased risk of aspiration or unable to swallow liquids
  • outside age range
  • non-consent to undertake treatment or follow up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IWK Health Centre

Halifax, Nova Scotia, B3K 6R8, Canada

Location

MeSH Terms

Conditions

Pain, PostoperativePostoperative Nausea and VomitingPersonal SatisfactionPostoperative Complications

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsNauseaSigns and Symptoms, DigestiveVomitingBehavior

Central Study Contacts

Jessica A Gray, MBBS, M.Med

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Randomised control trial into 1 of 2 groups
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator Jessica Gray

Study Record Dates

First Submitted

July 11, 2018

First Posted

August 20, 2018

Study Start

September 1, 2018

Primary Completion

February 1, 2020

Study Completion

June 1, 2020

Last Updated

August 21, 2018

Record last verified: 2018-08

Data Sharing

IPD Sharing
Will not share

Locations