Antibiotic Stewardship in Infectious Disease Departement

NCT03636711 | Unknown

• 1 other identifier: 2018-24
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Consensual antibiotic protocols have been developed and validated locally by infectious disease specialists, internists and emergency physicians, in order to encourage their compliance. A preliminary study was conducted from June 2015 to February 2016, including 622 patients admitted to the emergency department for infectious syndrome such as /

• Pneumoniae
• Urinary tract infection
• Cellulitis
• Meningitis
• Malaria
• Febrile neutropenia
• Febrile acute diarrhea
• Fever back to the tropics
• Angina
• sexually transmitted infection This prospective study will observe and analyze the adherence of prescribers to these protocols. With description of patients who benefited or not the antibiotic protocol, according to a syndromic approach and analysis of the causes of non-adherence to the protocols. In order to limit the length of stay and reduce the cost of hospitalization..

Conditions

Infectious Disease

Outcome Measures

Primary Outcomes (2)

• List of Antibiotic treatment

  Description of the prescribed antibiotic treatment depending of infectious syndrome: name, duration for each treatment during hospitalization Data will be collected in the medical files: * date of introduction of antibiotic treatment * withdrawal dates * stop dates * antibiotic classes

  up to 12 weeks

• Adverse events

  Description of the cause of non adherence to antibiotic treatment initiates at hospital admission of antibiotherapy: Data will be collected in the medical files of patients: events leading to withdrawal or stop treatment (insufficiency renal, allergic reaction ... etc) date of events aggravation or recovery

  up to 12 weeks

Study Arms (1)

experimental group

• Patient admitted to emergency for infectious syndrome Description of antibiotic protocol, according to a syndromic approach will be performed

Other: antibiotic protocol, according to a syndromic approach

Interventions

antibiotic protocol, according to a syndromic approach OTHER

Description of patients who benefited or not the antibiotic protocol, according to a syndromic approach and analysis of the causes of non-adherence to the protocols

experimental group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who present a infectious syndrom

You may qualify if:

• Patient admitted to emergency for infectious syndrome
• Patient \> 18 years old.
• Patient who accept to have his medical records reviewed for research.

You may not qualify if:

• Patient \< 18 years old.

Sponsors & Collaborators

• Assistance Publique Hopitaux De Marseille: lead

Study Sites (1)

Assistance Publique Des Hopitaux de Marseille

Marseille, PACA, 13005, France

Location

MeSH Terms

Conditions

Communicable Diseases

Condition Hierarchy (Ancestors)

Infections; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• EMILIE GARRIDO PRADALIE

  APHM

  STUDY DIRECTOR

Central Study Contacts

PHILIPPE PAROLA, MD

CONTACT

+33 491387235; Philippe.PAROLA@ap-hm.fr

CECILE LAVOUTE, PHD

CONTACT

+33 491381878; cecile.lavoute@ap-hm.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Days
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 9, 2018
• First Posted: August 17, 2018
• Study Start: September 1, 2018
• Primary Completion: July 1, 2021
• Study Completion: January 1, 2022
• Last Updated: August 17, 2018

Record last verified: 2018-08

Locations

FR (1)