Nutritional Care and Head Growth in Preterm Infants

NCT03635944 | Completed

• 1 other identifier: PICAUD JC
• Study Type: observational
• Target: 71
• Locations: 1 country
• Sites: 1

Brief Summary

As extremely low birth weight infants are high-risk patients, the study aimed to compare neonatal care, nutritional strategy and postnatal growth of these infants in two European neonatal units. A retrospective study included extremely low birth weight infants born in Lyon, France or in Stockholm, Sweden. Data on morbidity, treatments, care practices, macro-nutrient intakes and postnatal growth were collected to determine risk factors of extra uterine growth restriction at discharge. By comparing postnatal growth in ELBW infants hospitalized in two European neonatal intensive care units with different nutritional and extra nutritional care,our objective was to evaluate the role of nutrition in this population of preterm infants.

Conditions

Prematurity; Extreme; Growth Retardation

Keywords

growth; small for gestational age; prematurity; breastfeeding; fortification; parenteral nutrition; nutrition

Outcome Measures

Primary Outcomes (1)

• Weight gain during hospitalization

  difference in weight between birth and discharge

  between birth and 40 weeks

Secondary Outcomes (2)

• Crown-heel length gain during hospitalization

  between birth and 40 weeks

• Head circumference gain during hospitalization

  between birth and 40 weeks

Study Arms (2)

Group A

Infants born in Lyon (France)

Group B

Infants born in Stockholm (Sweden)

Eligibility Criteria

• Age: 1 Minute - 6 Months
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Extremely low birth weight infants born in two European tertiary care centres: neonatal unit of Croix Rousse Hospital in Lyon, France and the neonatal unit of Astrid Lindgren Children's Hospital in Stockholm, Sweden

You may qualify if:

• birth weight under 1000 grams
• gestational age (GA) between 23 and 28 weeks
• born in 2012
• admitted during the first 24 hours of life
• stayed in one of the two studied units for at least 7 weeks before transfer to the referring hospital, discharge to home or death.

You may not qualify if:

• Neonates with congenital anomalies

Sponsors & Collaborators

• Hôpital de la Croix-Rousse: lead

Study Sites (1)

Hopital de la croix rousse

Lyon, 69004, France

Location

MeSH Terms

Conditions

Premature Birth; Breast Feeding; Hyperphagia

Condition Hierarchy (Ancestors)

Obstetric Labor, Premature; Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Feeding Behavior; Behavior; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• jean-charles picaud, MD, PhD

  Hopital de la croix rousse

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor of pediatrics

Study Record Dates

• First Submitted: August 14, 2018
• First Posted: August 17, 2018
• Study Start: December 1, 2016
• Primary Completion: May 1, 2017
• Study Completion: July 1, 2018
• Last Updated: August 17, 2018

Record last verified: 2018-08

Locations

FR (1)