NCT03632707

Brief Summary

The aim of this study is to evaluate and analyze the role of magnetic resonance imaging in the diagnosis of medial meniscal posterior root tears, including the normal variations in meniscal anatomy that may resemble a meniscal tear, and identifying the causes or nature of posterior medial meniscal root tear(degenerative versus traumatic) and correlate the results with the standard reference knee Arthroscopy.In addition to identifying and estimating the suspected cases of meniscal extrusion by making MRI with stress varus overloading simulating weight bearing.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 13, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 15, 2018

Completed
6 months until next milestone

Study Start

First participant enrolled

February 1, 2019

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2022

Completed
Last Updated

February 17, 2022

Status Verified

January 1, 2022

Enrollment Period

2.9 years

First QC Date

August 13, 2018

Last Update Submit

February 16, 2022

Conditions

Medial Meniscus, Posterior Horn Derangement

Outcome Measures

Primary Outcomes (1)

  • Patients complain of painful knee joint associated with popping sounds and clinically suspected of medial meniscal posterior root tear will examined by Magnetic Resonance Imaging

    Correlation the results of Magnetic Resonance Imaging with gold standard knee Arthroscopy.

    6 months

Study Arms (1)

Magnetic resonance imaging of the knee

OTHER

Patients complain of painful knee with clinical suspicious of medial meniscus posterior root tear of the knee will be examined by all Magnetic Resonance Imaging sequences including sagittal, coronal and axial PD,T2 and PD-SPIR weighted images, and correlate the results with Knee Arthroscopy.while the suspected cases of meniscal extrusion will make MRI using the knee coil for varus stress Overloading simulating weight bearing.

Radiation: Magnetic Resonance Imaging of the kneeProcedure: Knee Arthroscopy

Interventions

Magnetic Resonance Imaging of the kneeRADIATION

After clinical assessment, all the patients will examined by Magnetic Resonance Imaging to diagnose the medial meniscal posterior root tear,and the suspected cases of meniscal extrusion will make MRI using the knee coil for varus stress Overloading simulating weight bearing

Magnetic resonance imaging of the knee
Knee ArthroscopyPROCEDURE

Correlate all the magnetic resonance imaging results with the Knee Arthroscopy

Magnetic resonance imaging of the knee

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients of either sex from more than 16 years, having acute or chronic painful knee associated with popping sounds are included in this study.

You may not qualify if:

  • Patients who are contraindicated to Magnetic Resonance Imaging examination as those who have artificial cardiac pacemaker or metallic prosthesis not compatible with Magnetic Resonance Imaging or those with severe claustrophobia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ashgan Ali Abdo Qardash

Asyut, Egypt

Location

Related Publications (4)

  • Barile A, Conti L, Lanni G, Calvisi V, Masciocchi C. Evaluation of medial meniscus tears and meniscal stability: weight-bearing MRI vs arthroscopy. Eur J Radiol. 2013 Apr;82(4):633-9. doi: 10.1016/j.ejrad.2012.10.018. Epub 2012 Nov 28.

    PMID: 23199751BACKGROUND

  • Park HJ, Kim SS, Lee SY, Choi YJ, Chung EC, Rho MH, Kwag HJ. Medial meniscal root tears and meniscal extrusion transverse length ratios on MRI. Br J Radiol. 2012 Nov;85(1019):e1032-7. doi: 10.1259/bjr/26261821.

    PMID: 23091292RESULT

  • Carreau JH, Sitton SE, Bollier M. Medial Meniscus Root Tear in the Middle Aged Patient: A Case Based Review. Iowa Orthop J. 2017;37:123-132.

    PMID: 28852346RESULT

  • Costa CR, Morrison WB, Carrino JA. Medial meniscus extrusion on knee MRI: is extent associated with severity of degeneration or type of tear? AJR Am J Roentgenol. 2004 Jul;183(1):17-23. doi: 10.2214/ajr.183.1.1830017.

    PMID: 15208101RESULT

Study Officials

  • Nisreen A. Abbas, MD

    Assiut University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

August 13, 2018

First Posted

August 15, 2018

Study Start

February 1, 2019

Primary Completion

January 1, 2022

Study Completion

February 1, 2022

Last Updated

February 17, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)