Opioid Use After Traumatic Injury in Adolescents
A Prospective Survey of Opioid Use After Traumatic Injury in Adolescents
1 other identifier
observational
123
1 country
1
Brief Summary
Currently, 1 in 8 adolescents continue to receive prescription opioids a year or more after injury. By longitudinally surveying patients, we can identify risk factors and pathways to nonmedical opioid use. Furthermore, by assessing whether pain management and mental health treatment after injury moderates sustained opioid use and prescription opioid misuse, we can create targeted interventions to reduce future nonmedical opioid use in adolescents.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jul 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2018
CompletedFirst Submitted
Initial submission to the registry
August 9, 2018
CompletedFirst Posted
Study publicly available on registry
August 14, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2023
CompletedMay 19, 2023
May 1, 2023
4.8 years
August 9, 2018
May 18, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Prospectively determine drivers of sustained opioid use and prescription opioid misuse.
2 years
Secondary Outcomes (4)
Identify patient-reported factors for sustained prescription opioid use, including chronic pain and mental health conditions such as PTSD, depression, anxiety, and sleep disorders.
2 years
Assess behavioral, social, and clinical predictors of prescription opioid misuse and nonmedical opioid use by longitudinally surveying injured adolescents.
2 years
Qualitatively determine patients' motives for continued opioid therapy, prescription opioid misuse, and nonmedical opioid use by interviewing injured adolescents.
2 years
Analyze genetic information, obtained via saliva sample and the company 23andMe, from each participant to determine if some people are more likely to use more pain medication than others or respond better to certain pain medications.
2 years
Study Arms (2)
Traumatically Injured Adolescent
Not Traumatically Injured Adolescent
Eligibility Criteria
Traumatically injured patients admitted to either Eskenazi Hospital or Riley Hospital, between the ages of 12 and 20.
You may qualify if:
- Patient is 12-20 years of age
- Adolescent admitted for trauma OR adolescent with no recent trauma
- English speaking
- Consent can be obtained from a parent or guardian
You may not qualify if:
- \- Patients with severe brain injuries or other injuries that prevent survey participation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Indiana University
Indianapolis, Indiana, 46202, United States
Biospecimen
Saliva will be collected at baseline only for the purpose of analyzing genetic data on each participant.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor of Health Policy
Study Record Dates
First Submitted
August 9, 2018
First Posted
August 14, 2018
Study Start
July 1, 2018
Primary Completion
March 31, 2023
Study Completion
April 30, 2023
Last Updated
May 19, 2023
Record last verified: 2023-05