NCT03628183

Brief Summary

This is a prospective, randomized, multicenter study to assess the tolerance of infant formulas.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
51

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 13, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 14, 2018

Completed
14 days until next milestone

Study Start

First participant enrolled

August 28, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 23, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 23, 2018

Completed
Last Updated

December 19, 2018

Status Verified

December 1, 2018

Enrollment Period

3 months

First QC Date

July 13, 2018

Last Update Submit

December 17, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Stool Characteristics

    Parent completed diary

    Study Day 1 - Study Day 21

Secondary Outcomes (3)

  • Formula Intake

    Study Day 1 - Study Day 21

  • Weight

    Study Day 1 - Study Day 21

  • Length

    Study Day 1 - Study Day 21

Study Arms (2)

Hydrolysate Infant Formula 1

ACTIVE COMPARATOR

Ready to feed infant formula in can

Other: Hydrolysate Infant Formula 1

Hydrolysate Infant Formula 2

EXPERIMENTAL

Ready to feed infant formula in bottle

Other: Hydrolysate Infant Formula 2

Interventions

Feed ad lib

Hydrolysate Infant Formula 1

Feed ad lib

Hydrolysate Infant Formula 2

Eligibility Criteria

AgeUp to 14 Days
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Subject is judged to be in good health
  • Singleton from a full-term birth
  • Birth weight was \> or = to 2490 g
  • Between 0 and 14 days of age at enrollment
  • Parent(s) confirm their intention to feed their infant the assigned study product as the sole source of nutrition for the duration of the study
  • Parent(s) confirm their intention not to administer vitamin or mineral supplements, solid foods or juices to their infant from enrollment through the duration of the study
  • Subject's parent(s) has voluntarily signed and dated an Informed Consent Form (ICF)

You may not qualify if:

  • An adverse maternal, fetal or subject medical history that is thought by the investigator to have potential for effects on tolerance, growth, and/or development.
  • Subject is taking and plans to continue medications, home remedies, herbal preparations or rehydration fluids that might affect gastrointestinal (GI) tolerance
  • Subject participates in another study that has not been approved as a concomitant study
  • Subject has an allergy or intolerance to any ingredient in the study product
  • Subject has been treated with antibiotics within 2 weeks prior to enrollment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Watching Over Mothers and Babies

Tucson, Arizona, 85712, United States

Location

Springs Medical Research

Owensboro, Kentucky, 42303, United States

Location

The Cleveland Pediatric Research Center, LLC

Cleveland, Ohio, 44130, United States

Location

Institute of Clinical Research, LLC

Mentor, Ohio, 44060, United States

Location

Midsouth Center for Clinical Research

Memphis, Tennessee, 38116, United States

Location

Study Officials

  • Courtney Allgeier, MS, RD, LD

    Abbott Nutrition

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 13, 2018

First Posted

August 14, 2018

Study Start

August 28, 2018

Primary Completion

November 23, 2018

Study Completion

November 23, 2018

Last Updated

December 19, 2018

Record last verified: 2018-12

Locations