Motor Interference Therapy For Traumatic Memories

NCT03627078 | Completed

• 1 other identifier: 69/17
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the effect of motor interference therapy (TIM) to reduce the intensity of discomfort (distress) generated by a traumatic memory compared to a relaxation control maneuver, immediately after the intervention, a week, a month and six months after intervention.

Conditions

Trauma, Psychological; Post Traumatic Stress Disorder

Keywords

traumatic memories; post traumatic stress disorder; motor interference therapy; non pharmacological therapy; trauma related disorders

Outcome Measures

Primary Outcomes (1)

• Change in Visual Analogue Scale (EVA)

  measures the distress related to traumatic memories in 1-10

  baseline, immediately, 1 week, 1 month, 6 months

Secondary Outcomes (2)

• Spanish version of the PTSD Symptom Severity Scale-Revised (EGS-R)

  baseline, 1 week, 1 month, 6 months

• visual analogue scale (EQ-VAS) from EuroQol 5D (EQ-5D)

  baseline, 1 week, 1 month, 6 months

Study Arms (2)

Motor Interference Therapy

EXPERIMENTAL

Initial interview applying the Spanish version of the PTSD Symptom Severity Scale-Revised (EGS-R), the visual analogue scale (EQ-VAS) from EuroQol 5D (EQ-5D), and a simple visual-analogue scale (VAS). After that, patients will listen to an audio track twice and follow the instructions. The first four minutes of the audio track instruct the subjects to tap their fingers in response to specific sounds. During the remaining ten minutes, the patients will be asked to recall a traumatic memory while simultaneously are tapping their fingers. Patients must complete at least 80% of the motor task in order to be included. We will reassess a week, a month and six months after the intervention, using all three scales.

Other: motor interference therapy

Relaxation Exercise

SHAM COMPARATOR

Initial interview applying the Spanish version of the PTSD Symptom Severity Scale-Revised (EGS-R), the visual analogue scale (EQ-VAS) from EuroQol 5D (EQ-5D), and a simple visual-analogue scale (VAS). After that, patients will listen to an audio track twice and follow the instructions. The first four minutes of the audio track instruct the subjects in how to do the exercises. During the remaining 10 minutes will hear commands for performing progressive muscle tension-relaxation exercises while the patient evoked the traumatic memory. Patients must complete at least 80% of the motor task in order to be included. We will reassess a week, a month and six months after the intervention, using all three scales.

Other: Relaxation exercises

Interventions

motor interference therapy OTHER

Also known as: TIM

Motor Interference Therapy

Relaxation exercises OTHER

In a top-down sequence, beginning with the upper body and proceeding to the lower parts. patients contract and relax a specific muscle group following the instructions given by the audio track. We use a shorter version that excludes the legs because of the time.

Also known as: Jacobson´s progressive relaxation

Relaxation Exercise

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients older than 16 years
• Spanish as a native language
• Give written informed consent
• having at least 1 traumatic memory causing distress

You may not qualify if:

• Neurological or psychiatric disorders that affect the capacity of verbal comprehension and judgment, such as dementia, psychosis, mental retardation or other cognitive alteration that does not allow them to perform the tasks indicated in the TIM or SHAM
• History of recent substance abuse
• Patients with significant hearing loss or some other hearing impairment

Sponsors & Collaborators

• El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez: lead

Study Sites (1)

Instituto Nacional de Neurologia Y Neurocirugia Mvs

Mexico City, Mexico City, 14269, Mexico

Location

Related Publications (1)

• Morales-Rivero A, Crail-Melendez D, Reyes-Santos L, Bisanz E, Bisanz J, Ruiz-Chow A, Chavarria-Medina MM. Effect of Motor Interference Therapy on Distress Related to Traumatic Memories: A Randomized, Double-Blind, Controlled Feasibility Trial. Brain Behav. 2024 Sep;14(9):e70063. doi: 10.1002/brb3.70063.

  PMID: 39317994 DERIVED

MeSH Terms

Conditions

Psychological Trauma; Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders

Study Officials

• Edgar D Crail-Melendez, MD

  El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.SC.

Study Record Dates

• First Submitted: August 8, 2018
• First Posted: August 13, 2018
• Study Start: March 1, 2016
• Primary Completion: March 30, 2019
• Study Completion: December 31, 2019
• Last Updated: July 29, 2020

Record last verified: 2020-07

Locations

ME (1)