NCT03625076

Brief Summary

This study compares intra-articular lidocaine to procedural sedation for the reduction of anterior shoulder dislocations in the emergency department.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
70

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jun 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2018

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

June 18, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

August 10, 2018

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 2, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

August 13, 2019

Status Verified

August 1, 2019

Enrollment Period

1.9 years

First QC Date

June 18, 2018

Last Update Submit

August 12, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Emergency Department Length of Stay

    The elapsed time over which the patient is physically in the emergency department

    Anticipated 1-4 hours

Secondary Outcomes (2)

  • Number of Reduction Attempts

    Each attempt takes under 5 minutes

  • Patient Satisfaction

    The patient is asked their satisfaction just prior to discharge (generally within 4 hours)

Study Arms (2)

Intra-articular Lidocaine

EXPERIMENTAL

20 mL of 1% lidocaine injected into the joint of the dislocated shoulder

Drug: Intra-articular Lidocaine

Procedural Sedation

ACTIVE COMPARATOR

Intravenous etomidate or propofol

Drug: Procedural Sedation with etomidate or propofol

Interventions

20 mL of 1% Lidocaine will be injected into the joint of the dislocated shoulder. Afterwards, the physician will attempt to reduce the shoulder using a technique of his or her choice.

Intra-articular Lidocaine

Procedural sedation using etomidate or propofol (physician's choice) will be performed. The dose of the drugs will also be left the treating physician. The physician will then attempt to reduce the shoulder using a technique of his or her choice.

Procedural Sedation

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients 18-70 years old in the emergency department with an anterior shoulder dislocation.

You may not qualify if:

  • Pregnant or breastfeeding
  • Is a prisoner.
  • Known allergy to one of the study drugs.
  • Altered mental status.
  • Shoulder fracture (other than a Hill-Sachs) associated with the dislocation.
  • Attending provider excludes patient.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kendall Regional Medical Center

Miami, Florida, 33175, United States

RECRUITING

MeSH Terms

Conditions

Shoulder Dislocation

Interventions

LidocaineEtomidatePropofol

Condition Hierarchy (Ancestors)

Joint DislocationsJoint DiseasesMusculoskeletal DiseasesWounds and InjuriesShoulder Injuries

Intervention Hierarchy (Ancestors)

AcetanilidesAnilidesAmidesOrganic ChemicalsAniline CompoundsAminesImidazolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsPhenolsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbons

Central Study Contacts

Tony Zitek, MD

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2018

First Posted

August 10, 2018

Study Start

June 1, 2018

Primary Completion

May 2, 2020

Study Completion

June 1, 2020

Last Updated

August 13, 2019

Record last verified: 2019-08

Locations