Zinc Supplement Before or With Food in Generally Healthy Men
Evaluation of Zinc Supplementation Taken Prior or With Food
1 other identifier
interventional
35
1 country
1
Brief Summary
The purpose of this study is to determine the influence of food consumption timing on the body's response to a zinc supplement
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Aug 2018
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 2, 2018
CompletedFirst Posted
Study publicly available on registry
August 7, 2018
CompletedStudy Start
First participant enrolled
August 21, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 15, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
April 15, 2019
CompletedMay 1, 2019
August 1, 2018
8 months
August 2, 2018
April 29, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Plasma Zinc changes
Change in plasma zinc
Day 0, Day 15
Secondary Outcomes (3)
Body weight changes
Day 0, Day 15
Essential Fatty acid changes
Day 0, Day 15
Blood glucose changes
Day 0, Day 15
Study Arms (2)
Supplement with food
EXPERIMENTALZinc supplement to be taken at time of breakfast consumption
supplement prior to food
EXPERIMENTALZinc supplement to be taken 30-min before breakfast consumption
Interventions
Eligibility Criteria
You may qualify if:
- willing to stop supplementation 4 weeks prior to start of the study
- has an operative understanding of English
- no plans to move from the area during the study period
- regularly eat breakfast
You may not qualify if:
- Chronic or acute metabolic disease
- smoker or user of nicotine products
- history of alcohol abuse, or use of illicit drugs (incl marijuana)
- Is underweight or overweight, body mass index (BMI) \< 18 or \> 30 kg/m2
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
UCSF Benioff Children's Hospital Oakland Research Institute
Oakland, California, 94609, United States
Related Publications (1)
Massih YN, Hall AG, Suh J, King JC. Zinc Supplements Taken with Food Increase Essential Fatty Acid Desaturation Indices in Adult Men Compared with Zinc Taken in the Fasted State. J Nutr. 2021 Sep 4;151(9):2583-2589. doi: 10.1093/jn/nxab149.
PMID: 34236435DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jung Suh, PhD
UCSF Benioff Children's Hospital Oakland Research Institute
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Masking Details
- Random number used to label samples
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 2, 2018
First Posted
August 7, 2018
Study Start
August 21, 2018
Primary Completion
April 15, 2019
Study Completion
April 15, 2019
Last Updated
May 1, 2019
Record last verified: 2018-08
Data Sharing
- IPD Sharing
- Will not share