Metabolic Equivalent of Task (MET) in the Preoperative Assessment in Aortic Surgery

NCT03617601 | Completed

• 1 other identifier: KEK-ZH-Nr: 2017-00801
• Study Type: observational
• Target: 296
• Locations: 0 countries
• Sites: N/A

Brief Summary

Reliable prediction of the preoperative risk is of crucial importance for patients undergoing vascular operations. The assessment of the metabolic equivalent of task (MET) is an easy clinical evaluation of the functional capacity of an individual. A MET is defined as the resting metabolic rate, that is the amount of the consumed oxygen at rest. According to the MET concept a patient would be considered as "fit for surgery" when the stairs of two flights can be climbed and the housework can be fully managed by oneself. Hypothesis: Patients with a functional capacity over 4 MET (fit for surgery) have less perioperative complications with the focus on cardiac pathology than patients with less than 4 MET during aortic operations. Patients and Method: Retrospective analysis of a single center unit of 296 patients undergoing open or endovascular aortic repair.

Conditions

Aortic Diseases

Outcome Measures

Primary Outcomes (1)

• Survival

  Mean survival during the whole follow up period of both groups, patients with less and more than 4 MET

  up to ten years

Secondary Outcomes (2)

• Perioperative complications

  up to 30 days postoperatively

• Coronary artery bypass grafting, percutaneous coronary intervention/Stenting

  up to ten years

Study Arms (2)

> 4 MET

Patients with functional capacity over 4 MET

Diagnostic Test: MET

< 4 MET

Patients with functional capacity under 4 MET

Diagnostic Test: MET

Interventions

MET DIAGNOSTIC_TEST

Testing of the metabolic equivalent of task before aortic procedure

< 4 MET; > 4 MET

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

296 patients who received an aortic repair with open or endovascular technique at Triemli Hospital from May 2009 till March 2016

You may qualify if:

• Data of all patients after open and endovascular aortic repair of the descending aorta from May 2009 till March 2016

You may not qualify if:

• Data of all patients with isolated operations on the ascending aorta or aortic arch

Sponsors & Collaborators

• Triemli Hospital: lead

Related Publications (1)

• Zientara A, Schwegler I, Dzemali O, Bruijnen H, Bernheim A, Dick F, Attigah N. Evaluation of metabolic equivalents of task (METs) in the preoperative assessment in aortic repair. BMC Surg. 2021 Mar 13;21(1):130. doi: 10.1186/s12893-021-01143-0.

  PMID: 33714271 DERIVED

MeSH Terms

Conditions

Aortic Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Nicolas Attigah, MD

  Triemli Hospital Zurich

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident for cardiac surgery

Study Record Dates

• First Submitted: July 6, 2018
• First Posted: August 6, 2018
• Study Start: May 1, 2009
• Primary Completion: August 1, 2016
• Study Completion: January 1, 2018
• Last Updated: August 6, 2018

Record last verified: 2018-07

Data Sharing

• IPD Sharing: Will not share