Trials Sponsors Conditions Drugs Pricing

Conditions

Avulsion Dental Trauma Periodontal Regeneration Pulpal Regeneration Topical Dexamethasone Topical Tetracycline

Outcome Measures

Primary Outcomes (2)

Number of teeth with periodontal regeneration
Periodontal regeneration was assessed with periodontal examination, percussion, Periotest measurements and periapical radiograph.
After a mean observation period of 12.9±2.4 years (one visit only)
Number of teeth with pulpal regeneration
Pulpal regeneration was assessed with periodontal examination, percussion, Periotest measurements, pulp sensitivity using CO2 snow and periapical radiograph.
After a mean observation period of 12.9±2.4 years (one visit only)

Secondary Outcomes (3)

Number of teeth that survived
After a mean observation period of 12.9±2.4 years (one visit only)

Study Arms (2)

Tetracycline

Teeth were soaked in topical tetracycline 5% for 5 minutes before replantation

Procedure: Tetracycline

Dexamethasone

Teeth were soaked in dexamethasone (60μ ml-1) for 20 minutes before replantation

Procedure: Dexamethasone

Interventions

TetracyclineProcedure

Teeth were soaked in topical tetracycline 5% for 5 minutes before replantation

Tetracycline

DexamethasoneProcedure

Teeth were soaked in topical dexamethasone (60μ ml-1) for 20 minutes before replantation

Dexamethasone

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age6 Years+

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients with avulsed permanent teeth who were treated between 2000-2008 at the Department of Oral Surgery, zmk Bern

You may qualify if:

Avulsion of a permanent tooth

Sponsors & Collaborators

University of Bern
Otherlead

Study Sites (1)

zmk Bern

Bern, 3010, Switzerland

MeSH Terms

Conditions

Fractures, Avulsion

Interventions

TetracyclineDexamethasone

Condition Hierarchy (Ancestors)

Fractures, BoneWounds and Injuries

Intervention Hierarchy (Ancestors)

TetracyclinesNaphthacenesPolycyclic Aromatic HydrocarbonsHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsOrganic Chemicals

Study Officials

Vivianne Chappuis, PD Dr.
Department of Oral Surgery and Stomatology, zmk Bern, University Bern
STUDY CHAIR

Enrollment

33 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

July 27, 2018

First Posted

August 2, 2018

Study Start

August 14, 2000

Actual (reported)

Effect of Topical Tetracycline and Dexamethasone on Periodontal and Pulpal Regeneration of Replanted Avulsed Teeth

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (3)

Study Arms (2)

Tetracycline

Dexamethasone

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (3)

Study Arms (2)

Tetracycline

Dexamethasone

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations