NCT03605017

Brief Summary

The purpose of this research is to investigate the effectiveness of a technique designed to improve divided attention and set-shifting impairments in persons with a traumatic brain injury (TBI). The study is designed to evaluate how well this technique can help people with TBI increase their attention and ability to function better in everyday life.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 26, 2014

Completed
4.3 years until next milestone

First Submitted

Initial submission to the registry

June 29, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 30, 2018

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 26, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 26, 2022

Completed
Last Updated

October 20, 2021

Status Verified

October 1, 2021

Enrollment Period

8 years

First QC Date

June 29, 2018

Last Update Submit

October 13, 2021

Conditions

Keywords

cognitive rehabilitationattentionexecutive function

Outcome Measures

Primary Outcomes (2)

  • Total divided attention post-treatment (covarying for baseline performance)

    Comparison between treatment and control groups on post-treatment Auditory Consonant Trigrams

    7 weeks (between pre- and post-testing)

  • Total set-shifting post-treatment (covarying for baseline performance)

    Comparison between treatment and control groups on post-treatment Stroop interference

    7 weeks (between pre- and post-testing)

Study Arms (2)

VREFT: Wonderkin Treatment

EXPERIMENTAL

Administered by computer

Behavioral: Virtual Reality Executive Function Training (VREFT)

VREFT: Attention Control

ACTIVE COMPARATOR

Administered by computer

Behavioral: Virtual Reality Executive Function Training (VREFT)

Interventions

VREFT: Attention ControlVREFT: Wonderkin Treatment

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • between the ages of 18-65
  • diagnosis of TBI
  • can read and speak English fluently

You may not qualify if:

  • prior stroke or neurological disease other than TBI
  • unstable or uncontrolled seizures
  • currently taking benzodiazepines

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kessler Foundation

East Hanover, New Jersey, 07936, United States

RECRUITING

MeSH Terms

Conditions

Brain Injuries, Traumatic

Condition Hierarchy (Ancestors)

Brain InjuriesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemWounds and Injuries

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Scientist

Study Record Dates

First Submitted

June 29, 2018

First Posted

July 30, 2018

Study Start

March 26, 2014

Primary Completion

March 26, 2022

Study Completion

March 26, 2022

Last Updated

October 20, 2021

Record last verified: 2021-10

Locations