NCT03604718

Brief Summary

Non-interventional Study to Assess the Safety and Effectiveness Profile of a SCIT Therapy With Beltavac® Polymerized With Alternaria alternata in allergic patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
65

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2018

Longer than P75 for all trials

Geographic Reach
1 country

13 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 7, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 19, 2018

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 27, 2018

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 20, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 20, 2023

Completed
Last Updated

May 11, 2023

Status Verified

May 1, 2023

Enrollment Period

4.6 years

First QC Date

July 19, 2018

Last Update Submit

May 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Numbers of treatment-related local and systemic reactions

    Number of adverse reactions occurred during the treatment period and classified according to the WAO standard

    1 year

Secondary Outcomes (3)

  • Rhinoconjuntivitis medication intake

    1 year

  • Visual analogue Scale Score

    1 year

  • IgE and IgG4 specific quantification

    1 year

Interventions

Adminstration of Beltavac® Polymerized with Alternaria alternata according to the routine clinical practice

Eligibility Criteria

Age5 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients from the age of 5 on, who suffer from allergic rhinoconjunctivitis caused by Alternaria alternata

You may qualify if:

  • Patients of the age of 5 years and older suffering from a clinically relevant Alternaria alternata induced allergic rhinitis
  • Positive skin testing or IgE determination to the relevant allergen

You may not qualify if:

  • Patients suffering from acute or chronic infections or inflammations Patients suffering from uncontrolled asthma Patients with a known autoimmune disease Patients with active malignant disease Patients requiring beta-blockers Patients having any contraindication for the use of adrenaline

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (13)

Universitary Hospital of Vic

Vic, Barcelona, Spain

Location

Medical Center Fedear

Barcelona, Catalonia, Spain

Location

University Hospital of Torrejon

Torrejón de Ardoz, Madrid, Spain

Location

University Hospital of Cartagena

Cartagena, Murcia, Spain

Location

Clínica de Alergia Mar Jiménez Lara

Talavera de la Reina, Toledo, Spain

Location

Allergo Centre

Barcelona, Spain

Location

Medical Center Cenvi Medic

Barcelona, Spain

Location

Alergomundo

Madrid, Spain

Location

Clinica Torrelodones

Madrid, Spain

Location

Ojeda Clinic

Madrid, Spain

Location

University Hospital Virgen de la Arrixaca

Murcia, 30100, Spain

Location

Reina Sofia Universitary Hospital

Murcia, Spain

Location

Clinica Alergologica Dr Moral

Toledo, Spain

Location

Study Officials

  • Inmaculada Buendía Jiménez

    Probelte Pharma

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 19, 2018

First Posted

July 27, 2018

Study Start

June 7, 2018

Primary Completion

January 20, 2023

Study Completion

January 20, 2023

Last Updated

May 11, 2023

Record last verified: 2023-05

Locations