NCT03599297

Brief Summary

Advancements in technology and endourological armamentarium provides multiple surgical options for complicated stone patients. To avoid multiple operations and shorten the total operation durations, bilateral synchronous simultaneous stone surgery (BSSSS) has been popularized in recent years. Our aim is to evaluate the preliminary outcomes of BSSSS in patients undergoing supine percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 4, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

July 26, 2018

Completed
1 month until next milestone

Study Start

First participant enrolled

September 1, 2018

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2024

Completed
Last Updated

August 7, 2023

Status Verified

August 1, 2023

Enrollment Period

5.3 years

First QC Date

June 4, 2018

Last Update Submit

August 3, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Stone free rate

    stone free status is decided according to both the immediate evaluation of the endoscopic view at the end of the operation and the post operative imaging with kidney, ureter, bladder X-ray at the 24th hour of the surgery

    at the 24th hour of the surgery

Secondary Outcomes (6)

  • Complications

    at the 1st week of surgery

  • Post operative urinary diversion

    at the 24th hour of surgery

  • Radiation exposure

    At 1st hour of surgery

  • Hemoglobin level change

    from baseline to 24th hour of surgery

  • Hospital stay

    will be assessed through completion of study, an average of 1 year.

  • +1 more secondary outcomes

Study Arms (1)

Bilateral synchronous simultaneous stone surgery

EXPERIMENTAL

Patients who will be operated for kidney stones at both their kidneys in a single surgery session will be included in the study. Patients will undergo percutaneous nephrolithotomy for one side and flexible ureteroscopy for the other side.

Procedure: Bilateral synchronous simultaneous stone surgery

Interventions

Patients undergoing Bilateral synchronous simultaneous stone surgery (one kidney undergoing percutaneous nephrolithotomy, other kidney undergoing ureteroscopy at the same time in a single patient)

Bilateral synchronous simultaneous stone surgery

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients scheduled for kidney stone surgery according to European Association Urology, Urolithiasis guidelines
  • patients with bilateral kidney stones

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Marmara University Hospital

Istanbul, 34890, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Kidney Calculi

Condition Hierarchy (Ancestors)

NephrolithiasisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrolithiasisUrinary CalculiMale Urogenital DiseasesCalculiPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Yiloren Tanidir, Ass. Prof.

    Marmara University, School of Medicine, Department of Urology

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yiloren Tanidir, Ass. Prof.

CONTACT

Tarik Emre Sener, Urologist

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2018

First Posted

July 26, 2018

Study Start

September 1, 2018

Primary Completion

December 31, 2023

Study Completion

February 1, 2024

Last Updated

August 7, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will not share

The data will not be shared.

Locations