Early Detection and Screening Strategy of Gatric Cancer in Sichuan Province-A Prospective Cohort Study (WCH-GC-SIGES-01)

NCT03597672 | Unknown

• 2 other identifiers: WCH-GC-SIGES-01320.2710.1815
• Study Type: observational
• Target: 30,000
• Locations: 1 country
• Sites: 1

Brief Summary

To establish prospective cohort of healthy population and corresponding serum sample bank in Sichuan province to provide platform for exploring early diagnosis and screening strategy of gastric cancer by a prospective cohort study.

Conditions

Neoplasm, Stomach; H. Pylori Infection; Chronic Atrophic Gastritis

Keywords

Gastric carcinoma; Early diagnosis; screening stragety; health population cohort

Outcome Measures

Primary Outcomes (1)

• The number of new cases of gastric carcinoma

  The new cases of gastric and other epidermal malignant tumor

  5 years

Secondary Outcomes (1)

• Time of finding nee cases

  5 years

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

In our study, the poplatiion was enrolled among health inhabitant in Sichuan province in China. People who underwent physical examination in our center who statisfy our indications will be introdeced to participate in our study. The informed consent will be endosed and the blood sample will be collected.

You may qualify if:

• Inhabitant in Sichuan province in China (length of residence \> 10 years);
• Complete physical examination in our hospital, the outcomes was asymptomatic and cancer free healthy individuals;
• Age between 20 and 70;
• With normal cognitive and communication ability;
• Without gastroscopy during recruitment, physical examination item including gastroscopy enrolled in prospective cohort study;
• Wiling to accept 1-2 times routine physical examination in our hospital;
• Agree to accept the follow-up of our project group;

You may not qualify if:

• With history of malignant tumor;
• Refuse to donate blood specimen;
• With serious comorbidity and/or finite life (less than 5 years);
• Request to retreat from this study;

Sponsors & Collaborators

• Jian-Kun Hu: lead
• Xin-Zu Chen: collaborator

Study Sites (1)

Jian-Kun Hu

Chengdu, Sichuan, 610041, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Serum samples

MeSH Terms

Conditions

Stomach Neoplasms; Gastritis, Atrophic; Disease

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases; Gastritis; Gastroenteritis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Jian-Kun Hu, M.D. Ph.D.

CONTACT

02885422878; hujkwch@126.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Vice director of Gastrointestinal Surgery department, West China Hospital; Director of Institute of Gastric Cancer, State Key Laboratory of Biotherapy, West China Hospital

Study Record Dates

• First Submitted: July 15, 2018
• First Posted: July 24, 2018
• Study Start: January 1, 2017
• Primary Completion: December 31, 2019
• Study Completion: December 31, 2020
• Last Updated: July 24, 2018

Record last verified: 2018-07

Locations

CN (1)