Meningitis With Cerebral Vasculitis in Children
Retrospective Study About 17 Cases of Child With Bacterial Meningitis Coupled With Cerebral Vasculitis
1 other identifier
observational
17
1 country
1
Brief Summary
Purulent meningitis are life-threatening diseases in childhood. Cerebral vasculitis have been described in bacterial meningitis, but poor is known about their physiology and their impact on outcome. The investigators decide to realize a retrospective mono-centric study carried out at Montpellier university hospital which looks back at a 7-year study(2009-2016). The Investigators selected purulent meningitis cases based on the bacteriological data provided by the HDB (hospital data base). The Investigators divides in two groups : Group A if patients present a cerebral vasculitis ( radiologic diagnostic by RMI or tomodensitometry), in all, cases the diagnosis of vasculitis was confirmed by a radiologist specialised in neuropaediatrics by a second reading;Group B purulent meningitis with a cerebral vasculitis imaging. Tuberculous meningitis, meningitis in CSF shunt, and in patients having chemotherapy were excluded. The investigators report clinical and biological finding, inflammatory marker at the onset. The Investigators register also the clinical evolution and sequelae
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2017
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2017
CompletedFirst Submitted
Initial submission to the registry
July 6, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2017
CompletedFirst Posted
Study publicly available on registry
July 23, 2018
CompletedJuly 26, 2018
July 1, 2017
2 months
July 6, 2017
July 23, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (5)
Found a difference demographic data
Found a difference demographic data between population A and B (age)
1 day
Found a difference demographic data
Found a difference demographic data between population A and B (gender)
1 day
Found a difference Clinical manifestation
Found a difference Clinical manifestation between population A and B
1 day
Found a difference Inflammatory parkers
Found a difference Inflammatory parkers between population A and B
1 day
Found a difference Infectious agent
Found a difference Infectious agent between population A and B
1 day
Secondary Outcomes (2)
Found a difference in the evolution of the diseases between group A and B
1 day
In the A group, studying the relationship between prescription of steroids pulse and final outcome and presence of sequelae.
1 day
Eligibility Criteria
Children with bacterial meningitis, and cerrbal vasculitis
You may qualify if:
- bacterial meningitis with LCR confirmation
You may not qualify if:
- tuberculous meningitis, immunosuppressor treatment, material like DVP
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Uhmontpellier
Montpellier, 34290, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Eric JEZIORSKI
UH
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 6, 2017
First Posted
July 23, 2018
Study Start
June 1, 2017
Primary Completion
August 1, 2017
Study Completion
August 31, 2017
Last Updated
July 26, 2018
Record last verified: 2017-07