NCT03594292

Brief Summary

The FASTFORWARDTM Bunion Correction system has been cleared by the United States Food and Drug Administration for sale. This study is to investigate the clinical outcome of MedShape FASTFORWARDTM Bunion Correction system in treating hallux valgus patients at CMUH. Criteria-There will be 12 subjects with a painful bunion and hallux valgus between 20 and 65 years of age and an adequate range of movement. Patients with rheumatoid arthritis, failed previous hallux valgus surgery and symptomatic and/or radiological arthritis of the MTP joint will be excluded. Protocol-The PI and SC explain the detail and purpose of the project to the patient to the language to the patient is comfortable with. The explanation has to be at least 1 hour. Be sure the patients understand the full detail before the surgery. Computer tomography scan, gait analysis and blood biochemical analysis will be taken in 1-2 weeks after patient is enrolled in the subject. Before surgery, the titration bone tether plate designed to match patent's second metatarsal contour will be manufactured using 3D printing technology. Printed titanium plate and PEEK screws used to secure tethering suture tape in the first metatarsal will be sterilized prior implantation. The surgery time, recovery period and effectiveness after implantation will be recorded. To observing the recovery situation, patients will back to out-patient clinic at 1st, 2nd, 3rd, 4th, 6th, 12th, 24th weeks. During these period, physical examination, wound dressing, VAS, X-ray scan will be arranged. The detail arrangements below: 1.1st week: physical examination, wound dressing, VAS 2.2nd week: physical examination, wound dressing, VAS 3.3rd week: physical examination, wound dressing, VAS, X-ray scan, remove stiches 4.4th week: physical examination, VAS 5.6th week: physical examination, VAS, X-ray scan 6.12th week: physical examination, VAS, X-ray scan 7.24th week: physical examination, VAS, X-ray scan, CT scan, gait analysis

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 31, 2018

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

June 24, 2018

Completed
26 days until next milestone

First Posted

Study publicly available on registry

July 20, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2019

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

July 20, 2018

Status Verified

January 1, 2018

Enrollment Period

8 months

First QC Date

June 24, 2018

Last Update Submit

July 18, 2018

Conditions

Keywords

hallux valgus and Bunion

Outcome Measures

Primary Outcomes (1)

  • Intermetatarsal 1-2 angle postoperative

    Evaluating the angle among the 1st and the 2nd metatarsal assess by X-ray scan and CT scan

    6 month

Secondary Outcomes (3)

  • Assessment Foot Pressure

    6 month

  • Pain using a visual analog scale

    6 month

  • Intermetatarsal 1-2 angle

    6 month

Study Arms (2)

FASTFORWARDTM Bunion

EXPERIMENTAL

The participants are treated with FASTFORWARDTM Bunion Correction system. The FASTFORWARDTM Bunion Correction system employed 3D printed titanium bone tether plate at second metatarsal. Due to the merit of 3D printing technology, the plate is designed to broadly distribute forces across bone to secure mechanical integrity of the bone. The FASTFORWARDTM Bunion Correction system has been cleared by the United States Food and Drug Administration.

Device: FASTFORWARDTM Bunion

Conventional Surgery

ACTIVE COMPARATOR

The participants are treated with fusion surgery. This procedures is a standard treatment for 1st metatarsal hallux valgus by cutting, realigning and fusing the 1st metatarsal or fusing the metatarsal-cuneiform joint.

Procedure: Conventional surgery

Interventions

The participants will be assign to implantation of FASTFORWARDTM Bunion correction system surgery as a experimental group.

FASTFORWARDTM Bunion

The participants will assign to conventional surgery as a control group, the procedure is a standard treatment for the 1st metatarsal hallux valgus.

Conventional Surgery

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with a painful bunion and hallux valgus between 20 and 65 years of age and an adequate range of movement

You may not qualify if:

  • Patients with rheumatoid arthritis, failed previous hallux valgus surgery and symptomatic and/or radio-logical arthritis of the MTP joint

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

China Medical University Hospital

Taichung, Beitun District, 404, Taiwan

RECRUITING

MeSH Terms

Conditions

Hallux ValgusBunion

Condition Hierarchy (Ancestors)

Foot DeformitiesMusculoskeletal DiseasesFoot Deformities, Acquired

Study Officials

  • Chien-Chung Kuo

    China Medical University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Physician, Department of Orthopedics

Study Record Dates

First Submitted

June 24, 2018

First Posted

July 20, 2018

Study Start

May 31, 2018

Primary Completion

February 1, 2019

Study Completion

December 1, 2019

Last Updated

July 20, 2018

Record last verified: 2018-01

Data Sharing

IPD Sharing
Will not share

Locations