NCT03591822

Brief Summary

Health care professionals lack tools to deal with acute pain in patients with moderate to severe dementia during daily nursing situations. Care-induced pain in institutionalized persons with cognitive impairments can cause anxiety and behavioral problems.The aim of this study is to demonstrate that a systematic identification of pain associated with the use of social robots such as the PARO robot may contribute to a better anticipation and management of care-induced pain. The investigators hypothesize that an individual use of the PARO robot would bring relaxation to the patient, a distraction regarding the aversive situation of care and, thus, it would prevent manifestations of acute pain in patients with dementia. Secondary objectives of the study :

  1. 1.determine the effect of the use of PARO during painful cares on quality of life, medication of patients, and perceived workload of the health-care team.
  2. 2.examine socio-demographic and clinical responders' participants to the intervention, and,
  3. 3.identify essential elements regarding cost-effectiveness of a systematic evaluation of pain and a mediation with the PARO robot in care-induced pain

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 9, 2018

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 19, 2018

Completed
7 months until next milestone

Study Start

First participant enrolled

February 15, 2019

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 12, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 12, 2019

Completed
Last Updated

September 12, 2025

Status Verified

September 1, 2025

Enrollment Period

2 months

First QC Date

July 9, 2018

Last Update Submit

September 5, 2025

Conditions

Keywords

DementiaPainNursing carePsychosocial interventionRobot-assisted therapyparo robot

Outcome Measures

Primary Outcomes (1)

  • ALGOPLUS scale

    A proximal measure of pain rating on a scale of 1) facial expressions, 2) look, 3) complaints, 4) body position and, 5) atypical behaviors. And a distal measures of pain

    2 months

Secondary Outcomes (13)

  • PACSLAC-F score

    at inclusion

  • PACSLAC-F score

    4 weeks

  • PACSLAC-F score

    8 weeks

  • Simple verbal scale (SVS)

    2 months

  • The appreciation of the Paro robot

    2 months

  • +8 more secondary outcomes

Study Arms (2)

Arm AB : Intervention under study x Control intervention

OTHER

Subjects receive intervention A during which they will benefit from a systemic pain assessment and from the PARO robot as a therapeutic mediator, followed by intervention B during which patients will benefit from a systemic pain assessment without the PARO robot.

Behavioral: A : Systemic evaluation of the pain and mediation with the PARO therapeutic robotBehavioral: B : Systemic evaluation of the pain

Arm BA: Control intervention x Intervention under study

OTHER

Subjects receive intervention B during which they will benefit from a systemic pain assessment without the PARO robot, followed by intervention A during which patients will benefit from a systemic pain assessment and from the PARO robot as a therapeutic mediator.

Behavioral: A : Systemic evaluation of the pain and mediation with the PARO therapeutic robotBehavioral: B : Systemic evaluation of the pain

Interventions

Each session with the PARO robot will encompasses the same four following steps (a) Meeting Paro (b) Proposing contact (c) Individually using Paro during the care (d) End of the exposure.

Arm AB : Intervention under study x Control interventionArm BA: Control intervention x Intervention under study

A systematic evaluation of the pain

Arm AB : Intervention under study x Control interventionArm BA: Control intervention x Intervention under study

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient over 60 years of age
  • Consent to participate
  • Patient diagnosed by a geriatrician or a neurologist with moderate to severe dementia (MMSE\<24), according to the criteria of the Diagnostic and Statistical Manual DSM IV-TR (APA,2004) and NINCDS-ADRDA(McKhann et al.1984).
  • Patient living in a nursing home or a long stay department
  • Painful patient during nursing care (pain drugs prescription or direct observation)

You may not qualify if:

  • Patient (or patient's legal representative) does not provide consent
  • The presence of acute organic disease or psychiatric decompensation and major neuropsychiatric symptoms incompatible with the intervention.
  • Patient who cannot interact physically with Paro
  • The presence of multidrug-resistant bacteria in patient to reduce the risk of contamination.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Résidence Mutualiste " L'adret "

Bellegarde-en-Forez, 42210, France

Location

Résidence Mutualiste " Les Tilleuls "

La Grand-Croix, 43320, France

Location

Hôpital Broca

Paris, 75013, France

Location

Résidence Mutualiste " La Cerisaie "

Saint-Etienne, 42000, France

Location

Résidence Mutualiste " Marie Lagrevol "

Saint-Just-Malmont, 43240, France

Location

Related Publications (1)

  • Demange M, Pino M, Kerherve H, Rigaud AS, Cantegreil-Kallen I. Management of acute pain in dementia: a feasibility study of a robot-assisted intervention. J Pain Res. 2019 Jun 7;12:1833-1846. doi: 10.2147/JPR.S179640. eCollection 2019.

    PMID: 31289446BACKGROUND

MeSH Terms

Conditions

DementiaPain

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Anne-Sophie RIGAUD, MD, PhD

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 9, 2018

First Posted

July 19, 2018

Study Start

February 15, 2019

Primary Completion

April 12, 2019

Study Completion

April 12, 2019

Last Updated

September 12, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations