Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation

NCT03591263 | Unknown

• 1 other identifier: 201805017RINB
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes obstructed airflow from the lung, characterized by chronic cough, dyspnea, and sputum production, which often misunderstood as aging or catching a cold. These symptoms may be progressive over time. To provide better disease management and early detecting, pulmonary rehabilitation is now considered a fundamental component of the integrated disease management of this population. However, few studies have evaluated the beneficial outcomes in patients referred to pulmonary rehabilitation. Therefore, the purpose of this study is to investigate the clinical outcomes in patients referred to pulmonary rehabilitation in National Taiwan University Hospital.

Conditions

Chronic Obstructive Pulmonary Disease

Outcome Measures

Primary Outcomes (9)

• Functional exercise capacity using the six-minute walk test

  The six-minute walk test is commonly performed to evaluate functional exercise capacity. The six-minute walk test was performed according to the guidelines, and the distance walked in the test presented as functional exercise capacity.

  The six-minute walk test needs six minute to complete the test

• Muscle strength: hand grip

  Hand grip strength is performed by using hand dynamometer

  Hand grip of both hands need about three minutes to complete

• Lung hygiene

  Lung hygiene is evaluated by the frequency of acute exacerbation

  Lung hygiene is evaluated as the frequency of acute exacerbation in the the past one year

• Home-based physical activity

  All subjects were encouraged to increase their daily physical activity and recorded the amount of physical activity on patient-self-record training log.

  Record the home-based physical activities everyday that the subjects have in the past one week that lasting for one year.

• Muscle strength: leg press

  Maximum leg press is performed by using seated leg press machine

  Maximum leg press measurement needs about four minutes to complete

• Heart rate

  Heart rate is measured at rest, during hospital-based physical training.

  Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously

• Blood pressure

  systolic and diastolic pressure are measured at rest, during hospital-based physical training.

  Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously

• Perceived dyspnea

  Rating of perceived dyspnea is measured by using Borg scale at rest, during hospital-based physical training, and home-based physical activity. The most widely used tool is the "Borg scale", with rating ranges from 0 (nothing at all) to 10 (extremely dyspnea).

  It takes less than one minute to evaluate perceived dyspnea.

• Oxygen saturation

  Oxygen saturation is continuously monitored by pulse oximetry throughout Hospital-based physical training.

  Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously

Study Arms (1)

Chronic obstructive pulmonary disease

Subjects with the diagnosis of chronic respiratory disease, such as chronic obstructive pulmonary disease, bronchiectasis, idiopathic pulmonary fibrosis that referred for evaluation as routine care at Physical Therapy Center (National Taiwan University)

Other: Pulmonary rehabilitation

Interventions

Pulmonary rehabilitation OTHER

Pulmonary rehabilitation as routine care includes, airway clearance techniques, breathing exercise, and physical training instruction

Chronic obstructive pulmonary disease

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with chronic respiratory disease: chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis.

You may qualify if:

• age \> 20 years old
• patients with chronic respiratory disease diagnosed by physician that referred to pulmonary rehabilitation in National Taiwan University Hospital including, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis
• can cooperate with pulmonary rehabilitation clinic

You may not qualify if:

• angina, acute myocardial infarction in the previous one month
• pregnancy

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

Physical Therapy Center at National Taiwan University Hospital

Taipei, Taiwan

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Li-Ying Wang, Phd

  National Taiwan University

  STUDY CHAIR

Central Study Contacts

Ping-Lun Hsieh

CONTACT

+886-905925933; 107673@ntuh.gov.tw

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 12, 2018
• First Posted: July 19, 2018
• Study Start: June 25, 2018
• Primary Completion: June 25, 2024
• Study Completion: June 25, 2024
• Last Updated: April 19, 2023

Record last verified: 2023-04

Locations

TW (1)