Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization
Assessment of Implementing Nano-technology in the Irrigation Protocol of One Step Revascularization For Necrotic Mature Teeth
1 other identifier
interventional
75
0 countries
N/A
Brief Summary
this study will assess different irrigating materials on the success revascularization of necrotic mature teeth associated with PRF.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable postoperative-pain
Started Sep 2018
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 26, 2018
CompletedFirst Posted
Study publicly available on registry
July 19, 2018
CompletedStudy Start
First participant enrolled
September 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2019
CompletedJuly 19, 2018
May 1, 2018
2 months
June 26, 2018
July 18, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
post-operative pain: Visual analogue scale
post-operative pain evaluated using Visual analogue scale , 0 no pain, 10 severe pain.
1 year
Secondary Outcomes (3)
periapical healing
1 year
sensitivity
1 year
survival
1 year
Study Arms (3)
propolis
EXPERIMENTALnatural antibacterial, anti-inflammatory irrigation solution
Nano-propolis
EXPERIMENTALnatural antibacterial, anti-inflammatory irrigation solution
saline
ACTIVE COMPARATORsodium chloride irrigation solution
Interventions
Using propolis as a final irrigation in revascularization
Using Nano-propolis as a final irrigation in revasculariztion
Using saline as a final irrigation in revasculariztion
Eligibility Criteria
You may qualify if:
- mature teeth.
- teeth with periapical periodontitis.
- Maxillary anterior teeth
- Patients should be free from any systemic disease
- Patients who will agree to the consent and will commit to follow-up period.
You may not qualify if:
- Patients with immature roots.
- Patients with any systemic disease that may affect normal healing.
- Patients with swelling. .Pregnant females. .Patients who could/would not participate in a 1-year follow-up. .Patients with fistula. .Patients with old age. .Teeth with periodontal involvement. .Teeth with vertical root fractures. .Non-restorable teeth.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principal investigator
Study Record Dates
First Submitted
June 26, 2018
First Posted
July 19, 2018
Study Start
September 1, 2018
Primary Completion
November 1, 2018
Study Completion
September 1, 2019
Last Updated
July 19, 2018
Record last verified: 2018-05