NCT03587623

Brief Summary

The study aim is to measure perioperative copeptin concentration in blood of liver transplant recipients and to assess whether there is a correlation between its level and hemodynamic derangement.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 3, 2018

Completed
1 day until next milestone

Study Start

First participant enrolled

July 4, 2018

Completed
12 days until next milestone

First Posted

Study publicly available on registry

July 16, 2018

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2020

Completed
Last Updated

August 19, 2020

Status Verified

August 1, 2020

Enrollment Period

1.6 years

First QC Date

July 3, 2018

Last Update Submit

August 15, 2020

Conditions

Liver CirrhosisCopeptinLiver Transplant

Outcome Measures

Primary Outcomes (1)

  • Serum Copeptin concentration

    Baseline, intraoperatively, 1,3,7,21 day postoperatively

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing liver transplant

You may qualify if:

  • \- Patient undergoing liver transplantation

You may not qualify if:

  • Serum creatinine \> 1,5 mg/dl
  • Retransplantation
  • Patient refusal
  • CRRT or dialysis preoperatively

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

I Klinika Anestezjologii WUM

Warsaw, Mazovian Voivodeship, 02-005, Poland

Location

MeSH Terms

Conditions

Liver CirrhosisDiabetes Insipidus

Condition Hierarchy (Ancestors)

Liver DiseasesDigestive System DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and SymptomsKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesPituitary DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 3, 2018

First Posted

July 16, 2018

Study Start

July 4, 2018

Primary Completion

January 31, 2020

Study Completion

January 31, 2020

Last Updated

August 19, 2020

Record last verified: 2020-08

Locations

PL(1)