Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial

You may not qualify if:

• Have pre-existing and documented conditions or concurrent diagnoses, including (and not necessarily limited to) active cancer, severe heart disease, significant cognitive impairment, eating disorders, significant psychiatric illness, end-stage COPD, severe pulmonary hypertension, or organ transplant.
• Concomitant use of interfering medication(s) or devices currently or within the month prior to enrollment, including anti-retrovirals, human monoclonal antibodies, supplemental daytime oxygen, and insulin pumps.
• Severe gastrointestinal issues or illnesses that would prevent adherence to the proposed diets.
• Severe kidney disease requiring dialysis
• Severe liver disease requiring frequent medical intervention
• Participating in other diet modification studies.
• High dose steroid (\>20mg prednisone or equivalent) or other hormonal treatments/chemotherapy use in the last month, including testosterone supplementation.
• Life-expectancy \< 6 months
• BMI ≥50 kg/m2 or ≤27 kg/m2
• Recent significant intentional or unintentional weight loss, defined as over 5% reduction in total body weight over the last month. (Blackburn Criteria).
• Significant or severe alcohol abuse disorder