NCT03577301

Brief Summary

YMHP is a counseling intervention program for which the goals are to better understand HIV-prevention focused self-management behaviors among HIV-negative YMSM, and to study the implementation of YMHP to improve portability and scalability. The clinic sites will help investigators to assess and address practical problems at the frontline of service provision to pave the way for a comprehensive program to reduce HIV infection among YMSM that reflects the complexities of real world adolescent HIV clinics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
83

participants targeted

Target at P25-P50 for not_applicable hiv-infections

Timeline
Completed

Started Oct 2018

Typical duration for not_applicable hiv-infections

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 6, 2018

Completed
3 months until next milestone

First Posted

Study publicly available on registry

July 5, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

October 4, 2018

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2022

Completed
2.3 years until next milestone

Results Posted

Study results publicly available

September 3, 2024

Completed
Last Updated

September 3, 2024

Status Verified

April 1, 2024

Enrollment Period

3.7 years

First QC Date

April 6, 2018

Results QC Date

May 30, 2023

Last Update Submit

April 5, 2024

Conditions

Keywords

HIVInterventionMen Who Have Sex with Men (MSM)PrEPYMHPYMSM

Outcome Measures

Primary Outcomes (3)

  • Illicit Drug Use Days

    The self-reported number of illicit drug use days (not including marijuana) in the past 30 days

    baseline, 3 months, 6 months, 9 months, 12 months

  • Condomless Anal Sex Acts

    The self-reported number of condomless anal sex acts with male partners in the last 30 days prior to assessment point.

    baseline, 3 months, 6 months, 9 months, 12 months

  • Marijuana Use Days

    The self-reported number of marijuana use days in the past 30 days prior to assessment point.

    baseline, 3 months, 6 months, 9 months, 12 months

Secondary Outcomes (1)

  • Alcohol Use Days

    baseline, 3 months, 6 months, 9 months, 12 months

Study Arms (4)

Clinic-based Delivery

ACTIVE COMPARATOR

Participants will receive the intervention in person following HIV counseling and testing. The intervention involves completion of the 4 YMHP sessions and the delivery of pre-exposure prophylaxis (PrEP) information and navigation services to interested participants. This arm is closed to enrollment.

Behavioral: Clinic-based Delivery

Remote Delivery

ACTIVE COMPARATOR

Participants will receive the intervention by remote delivery following HIV counseling and testing. Just as the clinic-based participants, he intervention involves completion of the 4 YMHP sessions and the delivery of pre-exposure prophylaxis (PrEP) information and navigation services to interested participants. This arm is closed to enrollment.

Behavioral: Remote Delivery

Multi-modal Delivery

ACTIVE COMPARATOR

A 4 session MI intervention. Session 1 is always delivered in person immediately after baseline. Session 2-4 can be delivered in person or remotely based upon youth preference. This arm is open to enrollment as of 11/15/2019.

Behavioral: Multi-modal Delivery

Treatment as Usual

NO INTERVENTION

Treatment as usual control = individual HIV testing with referrals and link age to care as provided by the sites under routine circumstances. This arm is open to enrollment as of 11/15/2019.

Interventions

A minimum of 2 community health workers (CHWs) will be trained to deliver clinic-based intervention sessions.

Clinic-based Delivery
Remote DeliveryBEHAVIORAL

A minimum of 2 community health workers (CHWs) will be trained to deliver intervention sessions to the participant in a location remote from the clinic setting.

Remote Delivery

A minimum of 2 community health workers (CHWs) will be trained to deliver clinic-based or remote intervention sessions. First MI session is in person immediately after baseline. Sessions 2-4 can be delivered in person or remotely based on youth preference.

Multi-modal Delivery

Eligibility Criteria

Age15 Years - 24 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsBorn biologically male or currently identifying as male
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • HIV-negative test result from the past 90 days
  • years of age
  • Born biologically male or currently identifying as male
  • Sex with men in the past 90 days
  • ≥ 3 days of illicit drug use in the past 90 days
  • ≥ 1 episode of Condomless Anal Sex (CAS) in the past 90 days, or a positive STI test result in the past 90 days.
  • Able to communicate in English

You may not qualify if:

  • Serious cognitive or psychiatric impairments
  • Currently taking Truvada as Pre-Exposure Prophylaxis (PrEP)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

University of Miami Miller School of Medicine

Miami, Florida, 33136, United States

Location

Wayne State University

Detroit, Michigan, 48202, United States

Location

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

HIV InfectionsHomosexuality

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesSexualitySexual BehaviorBehavior

Results Point of Contact

Title
Sylvie Naar, PhD; Distinguished Endowed Professor
Organization
Florida State University

Study Officials

  • Sylvie Naar, PhD

    Florida State University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 6, 2018

First Posted

July 5, 2018

Study Start

October 4, 2018

Primary Completion

May 31, 2022

Study Completion

May 31, 2022

Last Updated

September 3, 2024

Results First Posted

September 3, 2024

Record last verified: 2024-04

Locations