NCT03572985

Brief Summary

The purpose of this study is to collect alcohol calibration data for the driving simulator.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 19, 2018

Completed
8 days until next milestone

Study Start

First participant enrolled

June 27, 2018

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 28, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2019

Completed
Last Updated

February 28, 2025

Status Verified

November 1, 2019

Enrollment Period

7 months

First QC Date

June 19, 2018

Last Update Submit

February 26, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Standard Deviation of Lateral Position (SDLP)

    60 min

Secondary Outcomes (2)

  • Distance Coefficient of Variation (DCV)

    5 min

  • Brake Reaction Time (BRT)

    5 min

Study Arms (4)

Blood alcohol concentration (BAC) level 0.025 %

OTHER

Drink beverages containing alcohol calculated to have a blood alcohol concentration of 0.025%

Other: Road-tracking testOther: Car-following testOther: Harsh-braking test

BAC level 0.05 %

OTHER

Drink beverages containing alcohol calculated to have a blood alcohol concentration of 0.05%

Other: Road-tracking testOther: Car-following testOther: Harsh-braking test

BAC level 0.09 %

OTHER

Drink beverages containing alcohol calculated to have a blood alcohol concentration of 0.09%

Other: Road-tracking testOther: Car-following testOther: Harsh-braking test

BAC level 0 %

OTHER

Drink beverages containing non alcohol

Other: Road-tracking testOther: Car-following testOther: Harsh-braking test

Interventions

Driving with simulator program for SDLP measurement

BAC level 0 %BAC level 0.05 %BAC level 0.09 %Blood alcohol concentration (BAC) level 0.025 %

Driving with simulator program for DCV measurement

BAC level 0 %BAC level 0.05 %BAC level 0.09 %Blood alcohol concentration (BAC) level 0.025 %

Driving with simulator program for BRT measurement

BAC level 0 %BAC level 0.05 %BAC level 0.09 %Blood alcohol concentration (BAC) level 0.025 %

Eligibility Criteria

Age21 Years - 64 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Body mass index (BMI) ≥18.5 and \<25.0 kg/m\^2 at screening inspection
  • No visual impairment (enable to correct the vision with eyeglasses or contact lens)
  • Receive a prior explanation on the study, able to accept its content, and capable to provide voluntary written consent for participation in this study

You may not qualify if:

  • History of drug and food allergy
  • Alcohol dependence, drug dependence or abnormal drunken (including past history)
  • Inappropriate for enrollment in this study was judged by principal investigator or subinvestigator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Taisho Pharmaceutical Co., Ltd selected site

Fukuoka, Japan

Location

Related Publications (1)

  • Iwata M, Iwamoto K, Omura T, Ando M, Ozaki N. Protocol for the development and validation of a driving simulator for evaluating the influence of drugs on driving performance. Medicine (Baltimore). 2019 Feb;98(8):e14613. doi: 10.1097/MD.0000000000014613.

Study Officials

  • Shigeru Okuyama

    Taisho Pharmaceutical Co., Ltd.

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2018

First Posted

June 28, 2018

Study Start

June 27, 2018

Primary Completion

January 31, 2019

Study Completion

January 31, 2019

Last Updated

February 28, 2025

Record last verified: 2019-11

Locations