Addressing Overdose Risk Among Recently Incarcerated People Living With HIV/AIDS

NCT03569592 | Completed

• 1 other identifier: 1704005362
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The overall objective of this study is to evaluate an educational overdose prevention intervention's effectiveness among incarcerated people living with HIV/AIDS, specifically within the context of other outcomes related to health and experiences after incarceration. Results will be used to develop tailored interventions to reduce overdose deaths among high-risk correctional populations. The research has the following aims:

• Aim 1: Evaluate a pilot program to provide HIV+ inmates with 1:1 overdose prevention training while incarcerated;
• Aim 2: Identify the criminal justice, health, and HIV-related factors associated with overdose risk; and
• Aim 3: Describe the overdose risk experiences of HIV+ former inmates who use opioids after release.

Conditions

Drug Overdose Accidental

Keywords

HIV/AIDS; naloxone; incarceration

Outcome Measures

Primary Outcomes (2)

• Overdose knowledge

  The scale is adapted from the Opioid Overdose Knowledge Scale (OOKS). OOKS subscales measure overdose risks, signs, actions to take in a witnessed overdose, \& naloxone use. It has 4 multiple choice questions, 4 forced-choice questions, and 6 true/false statements. Each correct answer is 1 point and incorrect answers are 0. Subscale ranges are 0-9 for overdose risks, 0-10 for signs, 0-11 for actions to take in a witnessed overdose, and 0-15 for naloxone use. The total score range is summed from subscale scores from 0 to 45, with higher scores indicating greater knowledge. The adapted scale assesses the same domains and consists of 4 multiple choice questions, 1 forced-choice question, and 6 true/false statements. Each correct answer is 1 point and incorrect answers are 0. Subscale ranges are 0-5 for overdose risks, 0-4 for overdose signs, 0-5 for overdose actions, and 0-6 for naloxone use. Scores are summed for a total number of 20 points, with higher scores indicating greater knowled

  time of training until one month after release from jail

• Overdose attitudes

  The scale is adapted from the Opioid Overdose Attitudes Scale (OOAS). OOAS subscales measure overdose response competence (10 items), concerns (8 items), \& readiness (10 items). Likert scale options include "Completely Agree", "Agree", "Unsure", "Disagree", and "Completely Disagree" with a score of 1 to 5 assigned to each item. The total score range on the initial measure is summed from the subscales from 28-140 points (1-50 points on subscale competence, 1-40 points on subscale concerns, and 1-50 points on subscale readiness), with higher scores indicating favorable attitudes. The adapted scale also assesses: overdose response competence (4 questions), concerns (3 questions), and readiness (4 questions). Scoring is identical to the full scale, with possible subscales scores ranging from 1-20 for overdose competence, 1-15 for concerns about responding to an overdose, and 1-20 for readiness to respond to an overdose. Scores are summed for a total score range of 11-55. Higher scores in

  time of training until one month after release from jail

Secondary Outcomes (2)

• Witnessed overdoses

  1 month (release from jail until one month after release)

• Status of naloxone kit

  one month after release from jail

Study Arms (1)

Overdose Prevention Intervention

EXPERIMENTAL

The experimental group will receive a brief overdose prevention education intervention and be issues naloxone upon discharge from jail.

Behavioral: Overdose Prevention Intervention

Interventions

Overdose Prevention Intervention BEHAVIORAL

Evaluate an overdose prevention education with incarcerated people living with HIV/AIDS.

Also known as: Addressing Overdose Risk among Recently Incarcerated People Living with HIV/AIDS

Overdose Prevention Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• HIV-positive
• Age 18 and over
• Speaks English
• plans to live in Philadelphia area after release

You may not qualify if:

• More than 10 months remaining on a sentence or release date unknown

Sponsors & Collaborators

• Drexel University: lead

Study Sites (1)

Drexel University

Philadelphia, Pennsylvania, 19143, United States

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Incarcerated people living with HIV/AIDS will be given a brief training on overdose prevention and be given naloxone at discharge from jail.

Study Record Dates

• First Submitted: June 15, 2018
• First Posted: June 26, 2018
• Study Start: January 22, 2018
• Primary Completion: May 30, 2019
• Study Completion: January 31, 2020
• Last Updated: August 5, 2020

Record last verified: 2018-06

Locations

US (1)