NCT03568370

Brief Summary

The aim of the study is to evaluate the effectiveness of olive oil in the prevention of nipple cracking, nipple pain and ascension maternal satisfaction in lactating women. It's a prospective, randomized study of 80 lactating women, admitted to Tri-Service General hospital postpartum unit. Eligible patients were randomized to olive oil group or breast milk group and evaluate the effect of olive oil for nipple pain, nipple trauma, and maternal satisfaction.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2017

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 11, 2017

Completed
2 days until next milestone

Study Start

First participant enrolled

October 13, 2017

Completed
9 months until next milestone

First Posted

Study publicly available on registry

June 26, 2018

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2018

Completed
Last Updated

June 26, 2018

Status Verified

June 1, 2018

Enrollment Period

11 months

First QC Date

October 11, 2017

Last Update Submit

June 13, 2018

Conditions

Outcome Measures

Primary Outcomes (4)

  • Nipple pain change

    use Numeric Rating Scale 0-10 point

    Change from baseline nipple pain at 10 days

  • Nipple sore change

    use Nipple Soreness Score 0-5 point

    Change from baseline nipple pain at 10 days

  • Nipple trauma change

    use Nipple Trauma Score 0-5 point

    Change from baseline nipple trauma at 10 days

  • breastfeeding duration

    use Infant Feeding Categories

    30 days

Secondary Outcomes (1)

  • Maternal satisfaction

    baseline from Baseline nipple sore at 10 days

Study Arms (2)

olive oil

EXPERIMENTAL

use one drop olive oil on each nipple after each feeding

Other: olive oil

breast milk

NO INTERVENTION

use breast milk on each nipple after each feeding

Interventions

Evaluate the effectiveness of olive oil and human milk in the prevention of nipple cracking, nipple pain and maternal satisfaction in lactating women during the first 3 days of treatment and the 7th and 10th day after delivery.

Also known as: human milk
olive oil

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Normal spontaneous delivery.
  • Pregnancy weeks between 37-42.
  • Single birth.
  • Initiated breastfeeding.

You may not qualify if:

  • Presence of crack in the nipple.
  • Medication applied to the nipple
  • The maternal health condition that may interfere with breastfeeding.
  • The infant with congenital abnormalities that would impair breastfeeding.
  • The infant attained low birth weight or other criteria to intensive care unit.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lin

Taipei, Neihu, 114, Taiwan

RECRUITING

Related Publications (1)

  • Lin CX, Lu YY. Comparative Effectiveness of Olive Oil and Breast Milk on Nipple Soreness in Breastfeeding Mothers. Breastfeed Med. 2023 Oct;18(10):779-784. doi: 10.1089/bfm.2023.0081. Epub 2023 Oct 5.

MeSH Terms

Interventions

Olive OilMilk, Human

Intervention Hierarchy (Ancestors)

Dietary Fats, UnsaturatedDietary FatsFatsLipidsFats, UnsaturatedPlant OilsOilsFoodDiet, Food, and NutritionPhysiological PhenomenaFood and BeveragesMilkBeveragesDairy Products

Study Officials

  • Chen-Xi Lin

    lin050027@hotmail.com

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PI

Study Record Dates

First Submitted

October 11, 2017

First Posted

June 26, 2018

Study Start

October 13, 2017

Primary Completion

September 1, 2018

Study Completion

September 1, 2018

Last Updated

June 26, 2018

Record last verified: 2018-06

Locations