NCT03559322

Brief Summary

A Prospective, Observational, Post-market Surveillance Study to Evaluate the Long-term Safety and Efficacy of the iNAP® Lite Sleep Therapy System in Adults with Obstructive Sleep Apnea

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
76

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2019

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 6, 2018

Completed
12 days until next milestone

First Posted

Study publicly available on registry

June 18, 2018

Completed
1.1 years until next milestone

Study Start

First participant enrolled

August 1, 2019

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2021

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2021

Completed
Last Updated

September 23, 2019

Status Verified

September 1, 2019

Enrollment Period

2 years

First QC Date

June 6, 2018

Last Update Submit

September 19, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of participants with adverse events in this entire study.

    All safety events will be listed and tabulated for their occurrence rate

    through study completion, up to 10 weeks

Secondary Outcomes (1)

  • iNAP® Lite-treated clinical success rate

    a treated polysomnography or polygraphy assessment night

Interventions

Class II intraoral devices for snoring and/or obstructive sleep apnea

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults with obstructive sleep apnea in Taiwan

You may qualify if:

  • Diagnosed with OSA with AHI\>5

You may not qualify if:

  • Patients with central sleep apnea (CSA).
  • Patients with have severe respiratory disorders such as pulmonary diseases, pneumothorax, etc.
  • Patients with loose teeth or advanced periodontal disease.
  • Patients with pathologically low blood pressure.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shin Kong Wu Ho-Su Memorial Hospital

Taipei, 111, Taiwan

RECRUITING

Related Publications (1)

  • Lin HY, Nien CT, Chen CC, Hong II, Lin C, Lin CM. Optimizing treatment of the novel intra-oral negative pressure for obstructive sleep apnea. Sleep Breath. 2025 Feb 28;29(1):115. doi: 10.1007/s11325-025-03263-w.

Study Officials

  • Chung-Chu Chen, Ph.D.

    Somnics, Inc.

    STUDY CHAIR

Central Study Contacts

Chen-Ning Huang, Ph.D.

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 6, 2018

First Posted

June 18, 2018

Study Start

August 1, 2019

Primary Completion

August 1, 2021

Study Completion

December 30, 2021

Last Updated

September 23, 2019

Record last verified: 2019-09

Locations