NCT03559088

Brief Summary

The purpose of this study is to determine whether using a smart phone application to foster communication between study participants and their doctor will impact care. Participants must have a history of migraine or have recently been prescribed a common medicine to treat migraine. The study will last about one year for each participant.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2018

Geographic Reach
1 country

16 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 4, 2018

Completed
7 days until next milestone

Study Start

First participant enrolled

June 11, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 15, 2018

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 26, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 26, 2019

Completed
Last Updated

July 22, 2020

Status Verified

July 1, 2020

Enrollment Period

11 months

First QC Date

June 4, 2018

Last Update Submit

July 21, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants Receiving a Preventive Migraine Prescription

    Number of Participants Receiving a Preventive Migraine Prescription

    Next primary care appointment following use of app (estimated as 5 weeks)

Secondary Outcomes (8)

  • Number of Months of App Use

    Baseline through one year

  • Number of Participants Receiving Acute and Preventive Migraine Treatments, Opioids, Barbiturates

    Baseline through one year

  • Number of Acute Care Visits

    Baseline through one year

  • Number of Primary Care Visits

    Baseline through one year

  • Number of Emergency Room Visits

    Baseline through one year

  • +3 more secondary outcomes

Study Arms (2)

Migraine Participants Using Application (App)

EXPERIMENTAL

Participants with migraine history or a recent prescription for a common migraine medication will use a migraine app linked to their electronic health record (EHR) with results reported in their EHR.

Other: Migraine App

Controls Not Using App

NO INTERVENTION

Observational history on contemporaneous matched controls at similar sites without migraine app linked to their EHR.

Interventions

Smart phone app used to report migraine burden to the EHR.

Migraine Participants Using Application (App)

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have a diagnosis of migraine (ICD10: G43.\*) since October 2015 OR a record of being prescribed a triptan prior to study
  • Have not been prescribed a preventive migraine medication within the past twelve months
  • Have not visited a neurologist in the past year
  • Have an upcoming visit with their Atrium Health primary care provider

You may not qualify if:

  • Do not own an iOS or Android smart phone with a data plan or are unwilling to install the app on their phone
  • Are currently participating in a clinical trial involving an investigational drug
  • Have previously used the app used in this study
  • Are pregnant at the time of study entry
  • Are not able to provide informed consent
  • Cannot speak and read English fluently

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (16)

Charlotte Internal Medicine

Charlotte, North Carolina, 28202, United States

Location

Charlotte Medical Clinic

Charlotte, North Carolina, 28203-5812, United States

Location

Carmel Family Physicians

Charlotte, North Carolina, 28210, United States

Location

Charlotte Medical Clinic-South Park

Charlotte, North Carolina, 28211, United States

Location

Randolph Internal Medicine

Charlotte, North Carolina, 28211, United States

Location

South Charlotte Primary Care

Charlotte, North Carolina, 28226, United States

Location

Mecklenburg Medical Group - Ballantyne

Charlotte, North Carolina, 28277, United States

Location

Table Rock Family Medicine

Glen Alpine, North Carolina, 28628, United States

Location

Mecklenburg Medical Group - Northcross

Huntersville, North Carolina, 28078, United States

Location

North Charlotte Medical Specialists - Huntersville

Huntersville, North Carolina, 28078, United States

Location

Lincoln Family Practice

Lincolnton, North Carolina, 28092, United States

Location

Mecklenburg Medical Group - Matthews

Matthews, North Carolina, 28105, United States

Location

Union Family Practice

Monroe, North Carolina, 28112, United States

Location

Troy Medical Services

Troy, North Carolina, 27371, United States

Location

Shiland Family Fort Mill

Fort Mill, South Carolina, 29715, United States

Location

Shiland Family Practice

Fort Mill, South Carolina, 29715, United States

Location

MeSH Terms

Conditions

Migraine Disorders

Condition Hierarchy (Ancestors)

Headache Disorders, PrimaryHeadache DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

    Eli Lilly and Company

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2018

First Posted

June 15, 2018

Study Start

June 11, 2018

Primary Completion

April 26, 2019

Study Completion

April 26, 2019

Last Updated

July 22, 2020

Record last verified: 2020-07

Locations