Impact of the Introduction of a Gastro-intestinal Panel by Polymerase Chain Reaction (PCR).
1 other identifier
observational
210
1 country
1
Brief Summary
Evaluation of the impact of the introduction of multiplex PCR panels on the clinical management of patients with gastroenteritis at the University Hospital of Lausanne, Switzerland.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2018
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2018
CompletedFirst Submitted
Initial submission to the registry
May 28, 2018
CompletedFirst Posted
Study publicly available on registry
June 11, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
March 30, 2020
CompletedOctober 23, 2020
October 1, 2020
10 months
May 28, 2018
October 22, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Prescription of antibiotics
Number of patients receiving a prescription of antibiotics depending on the type of investigation
Within 1 week of availability of stool result
Secondary Outcomes (3)
Pathogens identified
1 day
Number of PCR tests requested.
1 month
Additional investigations
1 week
Study Arms (2)
Traditional methods
Patients, who consulted for gastro-intestinal symptoms between July 2016 and May 2017, and were investigated by traditional methods (stool microscopy and/or culture).
Gastro-intestinal panel by PCR
Patients, who consulted for gastro-intestinal symptoms between July 2017 and May 2018,and were investigated by a gastro-intestinal panel by PCR
Interventions
The study will evaluate the change in medical management with the replacement of traditional stool investigations (microscopy and culture) by the new gastrointestinal multiplex PCR panels
Eligibility Criteria
Patients consulting the emergency department of the University Hospital of Lausanne for gastro-intestinal symptoms suggestive of an infectious origin
You may qualify if:
- Ambulatory patients who consulted the University Hospital of Lausanne between July 2016 and May 2017, and were investigated by traditional methods (stool microscopy and culture).
- Ambulatory patients who consulted the University Hospital of Lausanne between July 2017 and May 2018 and had stool investigations by a gastro-intestinal panel.
You may not qualify if:
- Patients for whom there ia record in the file that they do not accept that their data are used for research purposes.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Outpatient Care and Community Medicine, University Hospital of Lausanne
Lausanne, 1011, Switzerland
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Serge de Valliere, MD,MSc
University of Lausanne Hospitals
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PD & MER
Study Record Dates
First Submitted
May 28, 2018
First Posted
June 11, 2018
Study Start
March 1, 2018
Primary Completion
December 31, 2018
Study Completion
March 30, 2020
Last Updated
October 23, 2020
Record last verified: 2020-10