Neural Correlates of Self-regulation on Academic Functioning

NCT03549377 | Completed

• 1 other identifier: 44065
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The main objectives of the study include: 1. What are the differences in self-regulation and its neurophysiological and neuroanatomical correlates between college students with poor and excellent sleep functioning? 2. Does sleep functioning (assessed both by questionnaires and actigraphy), and self-control/self-regulation (questionnaire and imaging data) predict academic achievement and problem behaviors in college students?

Conditions

Self-Control

Keywords

Sleep; Academic functioning; Problem behaviors; College age youth; Self-regulation

Outcome Measures

Primary Outcomes (4)

• Rested versus sleep deprived group differences of Functional magnetic resonance imaging (fMRI) Blood oxygenation level dependent (BOLD) responses for Stop Signal Reaction Time Task (SSRT) Stop Signals

  Rested versus sleep deprived group differences of functional magnetic resonance imaging reactivity of the whole brain while performing a Stop Signal Reaction Time Task

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

• Rested versus sleep deprived group differences of fMRI BOLD responses for a Go-NoGo Continuous Performance Task (CPT)

  Rested versus sleep deprived group differences of functional magnetic resonance imaging reactivity of the whole brain while performing a Go-NoGo Continuous Performance Task

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

• Rested versus sleep deprived group differences of brain structural connectivity

  Rested versus sleep deprived group differences of brain structural connectivity as measured by diffusion tensor imaging and analyzed using tract-based spatial statistics

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

• Rested versus sleep deprived group differences of brain structure

  Rested versus sleep deprived group differences of brain structure as determined by voxel based morphometry of structural magnetic resonance imaging data

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

Other Outcomes (15)

• Rested versus sleep deprived group differences in sleep time preferences

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

• Rested versus sleep deprived group differences in hours of sleep

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional studyUp to 45 days following selection for inclusion based on prescreen, cross-sectional study

• Rested versus sleep deprived group differences in low self-control

  Up to 45 days following selection for inclusion based on prescreen, cross-sectional study

Study Arms (2)

Rested

Based on Pittsburgh Sleep Quality Index, participants scoring in the top 10-20% will be assigned to the rested group and will experience deception as part of the delayed gratification task

Behavioral: Deception

Sleep-deprived

Based on Pittsburgh Sleep Quality Index, participants scoring in the bottom 10-20% will be assigned to the sleep-deprived group and will experience deception as part of the delayed gratification task

Behavioral: Deception

Interventions

Deception BEHAVIORAL

Participants will be deceived during delayed gratification task.

Rested; Sleep-deprived

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study sample will consist of 24 healthy college students (12 males and 12 females) between ages 18 - 24 years.

You may qualify if:

• Healthy college-age youth between the ages of 18 and 24 years

You may not qualify if:

• Gross impairment of vision or hearing
• Inability to read and follow written instructions
• Physical, neurological, or concurrent psychiatric impairments
• Regular intake of psychotropic medication (such as methylphenidate used to treat Attention Deficit Hyperactivity Disorder (ADHD), antidepressants, or anti-anxiety medication)
• A history of head injury that resulted in loss of consciousness/a history of brain surgery/or seizures
• A current/past history of smoking and/or alcohol or drug abuse (i.e., five or more drinks in one sitting or 15 drinks or more during a week for men, and four drinks on one occasion or eight drinks over the course of a week for women; additionally, regular drug use, including marijuana)
• Current pregnancy
• Any metallic objects in your body (such as braces, pacemakers, surgical devices, piercings that cannot be removed etc.) Enrollment of the subjects will start in May 2018 and will be finished by the end of December 2018.

Sponsors & Collaborators

• Alexander Vazsonyi: lead

Study Sites (1)

University of Kentucky

Lexington, Kentucky, 40506, United States

Location

Related Publications (4)

• Gottfredson MR, Hirschi T. A general theory of crime. Stanford: Stanford University Press; 1990.

  BACKGROUND

• Steinberg L, Albert D, Cauffman E, Banich M, Graham S, Woolard J. Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: evidence for a dual systems model. Dev Psychol. 2008 Nov;44(6):1764-78. doi: 10.1037/a0012955.

  PMID: 18999337 BACKGROUND

• Owens JA, Dearth-Wesley T, Lewin D, Gioia G, Whitaker RC. Self-Regulation and Sleep Duration, Sleepiness, and Chronotype in Adolescents. Pediatrics. 2016 Dec;138(6):e20161406. doi: 10.1542/peds.2016-1406. Epub 2016 Nov 3.

  PMID: 27940688 BACKGROUND

• Wheaton AG, Jones SE, Cooper AC, Croft JB. Short Sleep Duration Among Middle School and High School Students - United States, 2015. MMWR Morb Mortal Wkly Rep. 2018 Jan 26;67(3):85-90. doi: 10.15585/mmwr.mm6703a1.

  PMID: 29370154 BACKGROUND

MeSH Terms

Conditions

Self-Control; Problem Behavior

Condition Hierarchy (Ancestors)

Social Behavior; Behavior; Behavioral Symptoms; Child Behavior

Study Officials

• Alexander T Vazsonyi, Ph.D.

  University of Kentucky

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Endowed Professor

Study Record Dates

• First Submitted: May 14, 2018
• First Posted: June 8, 2018
• Study Start: May 11, 2018
• Primary Completion: August 31, 2019
• Study Completion: August 31, 2019
• Last Updated: September 17, 2019

Record last verified: 2019-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)