Trials Sponsors Conditions Drugs Pricing

Conditions

Temperature; Extreme, Exposure

Keywords

temperature

Outcome Measures

Primary Outcomes (1)

Clinical pregnancy
ultrasound: sac and fetal heartbeat positive
7 weeks

Secondary Outcomes (4)

Fertilization rate
1 day
embryo development/utilization rate
6 days
live birth rate of the fresh cycle
43 weeks
cumulative live birth rate per cycle
104 weeks

Study Arms (2)

36.6°C

ACTIVE COMPARATOR

Embryos of these patients will be cultured at 36.6°C from day 0 after ICSI, untill day 6.

Device: G210 incubator

37.1°C

EXPERIMENTAL

Embryos of these patients will be cultured at 37.1°C from day 0 after ICSI, untill day 6.

Device: G210 incubator

Interventions

G210 incubatorDevice

very stable culture temperature, up to 0.1°C, in both arms

Also known as: Ksystems

36.6°C37.1°C

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 40 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Day 5 transfer
Single embryo transfer

Sponsors & Collaborators

Universitair Ziekenhuis Brussel
Otherlead

Study Sites (1)

Universitair Ziekenhuis Brussel

Brussels, Brussels Capital, 1090, Belgium

Related Publications (1)

Wouters K, Mateizel I, Segers I, Van de Velde H, Van Landuyt L, De Vos A, Schoemans C, Jankovic D, Blockeel C, Drakopoulos P, Tournaye H, De Munck N. Clinical pregnancy rates after blastocyst culture at a stable temperature of 36.6 degrees C versus 37.1 degrees C: a prospective randomized controlled trial. Hum Reprod. 2024 Oct 1;39(10):2233-2239. doi: 10.1093/humrep/deae193.
PMID: 39241807DERIVED

Study Officials

Greta Verheyen, PhD
UZBrussel
STUDY DIRECTOR

Enrollment

234 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: DIAGNOSTIC
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: PhD

Study Record Dates

First Submitted

October 23, 2017

First Posted

June 7, 2018

Study Start

November 1, 2017

Embryo Culture At a Constant Temperature of 36.6°C or 37.1°C

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

36.6°C

37.1°C

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

36.6°C

37.1°C

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations