NCT03544086

Brief Summary

The primary endpoint is to evaluate the sensitivities and specificities for diagnosis of sleep apnoea of a wearable sleep diagnosis technology vs. existing gold standard.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2018

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 22, 2018

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 1, 2018

Completed
1 month until next milestone

Study Start

First participant enrolled

July 10, 2018

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2019

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2020

Completed
Last Updated

December 4, 2020

Status Verified

December 1, 2020

Enrollment Period

1.5 years

First QC Date

May 22, 2018

Last Update Submit

December 3, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sensitivities and Specificities for diagnosis of sleep apnoea studies

    Sensitivities and Specificities for diagnosis of sleep apnoea studies

    6 months

Study Arms (2)

test group

First group is the first 10 patients

study group

following 150 patients

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who have been referred to a sleep clinic due to suspicion of sleep apnoea, consecutive 160 patients coming to the clinic.

You may qualify if:

  • Patients who have been referred to a sleep clinic due to suspicion of sleep apnoea.

You may not qualify if:

  • Age under 18 or over 70 years.
  • Subjects who are not fluent in English, or who have special communication needs.
  • Known allergy to the adhesive dressing.
  • Subjects with physical or mental impairments who would not be able to use the new technology on their own.
  • Subjects with very loose/saggy skin in the neck area which would unavoidably result on - AcuPebble swinging if moving the neck.
  • Subjects with pacemakers.
  • exclude patients who have any type of implanted electronic devices (these include patients in ICDs and left ventricular assist devices and loop recorders).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Royal Free Hospital

London, United Kingdom

Location

Related Publications (1)

  • Devani N, Pramono RXA, Imtiaz SA, Bowyer S, Rodriguez-Villegas E, Mandal S. Accuracy and usability of AcuPebble SA100 for automated diagnosis of obstructive sleep apnoea in the home environment setting: an evaluation study. BMJ Open. 2021 Dec 21;11(12):e046803. doi: 10.1136/bmjopen-2020-046803.

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Dr Swapna Mandal, BSc MBBS MRCP SCE, PhD

    Royal Free NHS Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 22, 2018

First Posted

June 1, 2018

Study Start

July 10, 2018

Primary Completion

December 30, 2019

Study Completion

September 15, 2020

Last Updated

December 4, 2020

Record last verified: 2020-12

Data Sharing

IPD Sharing
Will not share

Locations