NCT03543345

Brief Summary

Proximal RCA occlusions were very often found among men with fatal pre-hospital MI; whereas left-sided coronary occlusions were significantly more frequent in hospital-admitted survivors of MI. Left-sided coronary occlusions may be associated with a more favorable pre-hospital phase of acute MI compared to proximal RCA occlusions. Proximal RCA occlusion increases the risk of arrhythmia and shock leading to increase the mortality. Sinus bradycardia and cardiogenic shock accounts for the majorities of the mortalities of RCA occlusion

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 21, 2018

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 1, 2018

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2018

Completed
13 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 28, 2018

Completed
Last Updated

June 19, 2018

Status Verified

June 1, 2018

Enrollment Period

3 months

First QC Date

May 21, 2018

Last Update Submit

June 16, 2018

Conditions

Keywords

RCAPCIright ventricular function

Outcome Measures

Primary Outcomes (1)

  • Change in RV function PCI to RCA

    The aim of the study is to determine the impact of elective PCI of RCA on RV systolic and diastolic functions.

    3 months

Interventions

echocardiography studyDIAGNOSTIC_TEST

Patients with right coronary artery occlusion lesion will be subjected to: * Written consent. * Complete history. * Complete physical examination. * Trans-thoracic echocardiography assessment of the right ventricular function before PCI to the RCA * Follow up Trans-thoracic echocardiography assessment of the right ventricular function four weeks after the PCI.

Eligibility Criteria

Age40 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients subjected to elective PCI due to right coronary artery occlusion. Patients between 40 and 75 years old from the both genders

You may qualify if:

  • Patients subjected to elective PCI due to right coronary artery occlusion. Patients between 40 and 75 years old from the both genders

You may not qualify if:

  • History of chronic respiratory condition and PHTN
  • Patients with previous percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG).
  • History of valvular surgery.
  • Patients with significant rheumatic vavular heart disease.
  • Presence of persistant arrythemia
  • Patients with End stage renal disease.
  • Patients with End stage liver disease.
  • Haemodynamically unstable patients.
  • Patients with previous Myocardial infarction.
  • Patients with Ischemic Dilated Cardiomyopathy.
  • Patients with pericardial disease.
  • Patients with congenital intra-cardiac shunt.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Al Azhar university

Asyut, Egypt

RECRUITING

Central Study Contacts

Hazim A. Kaml, MBcCH

CONTACT

Mahmoud A. Abd Elbaset, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

May 21, 2018

First Posted

June 1, 2018

Study Start

June 1, 2018

Primary Completion

August 15, 2018

Study Completion

August 28, 2018

Last Updated

June 19, 2018

Record last verified: 2018-06

Locations