NCT03525938

Brief Summary

the study will evaluate the effect of transversus abdominis plane block (TAP) on chronic post-groin surgeries orchalgia (chronic testicular pain)

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2018

Completed
11 days until next milestone

Study Start

First participant enrolled

May 10, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 16, 2018

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2019

Completed
Last Updated

July 8, 2019

Status Verified

July 1, 2019

Enrollment Period

1.4 years

First QC Date

April 29, 2018

Last Update Submit

July 3, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • The change of intensity of pain measured by Visual Analogue Pain (VAS ) score

    The Visual Analogue Pain (VAS) scale is a tool for intensity of pain scored from 0 to 10, where 0 = no pain and 10 = the worst pain imaginable

    The pain assessment will be done one month, 2 month and 3 month postprocedure.

Study Arms (2)

TAP group

ACTIVE COMPARATOR
Procedure: TAP block

SHAM group

SHAM COMPARATOR
Procedure: TAP block

Interventions

TAP blockPROCEDURE

Whilst the patient is in the supine position, a high frequency ultrasound probe (10 MH) is placed transverse to the abdominal wall between the costal margin and iliac crest. The needle is introduced in plane of the ultrasound probe directly under the probe and advanced until it reaches the plane between the internal oblique and transversus abdominis muscles. Upon reaching the plane, 2 ml of saline is injected to confirm correct needle position after which 20 ml of levobupivacaine, 25% plus triamcinolone, 80 mg solution is injected for TAP group and 20 ml of saline only is injected for SHAM group.. The transversus abdominis plane is visualized expanding with the injection ( appears as a hypoechoic space)

SHAM groupTAP group

Eligibility Criteria

Age18 Years - 80 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • pain intensity ≥ 5 on the visual analog scale (VAS),
  • pain that lasted for more than 3 months after groin surgeries,
  • failed conservative treatment with nonsteroidal anti-inflammatory drugs (NSAIDs)

You may not qualify if:

  • patients with other causes of scrotal pain, e.g., epididymitis, orchitis, and hydrocele,
  • patients complaining of groin infection and coagulopathy,
  • patients suffering from hypertension, ischemic heart disease, or psychiatric disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Diab

Asyut, Assuit, 71515, Egypt

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assuit university, south egypt cancer institute, anesthesia department

Study Record Dates

First Submitted

April 29, 2018

First Posted

May 16, 2018

Study Start

May 10, 2018

Primary Completion

October 15, 2019

Study Completion

November 25, 2019

Last Updated

July 8, 2019

Record last verified: 2019-07

Locations