Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

NCT03524521 | Completed

• 1 other identifier: 17-010163
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.

Conditions

Body Weight Changes; Overweight and Obesity; Physical Activity

Outcome Measures

Primary Outcomes (1)

• Change in Body fat percent

  DEXA derived body fat %

  12 weeks

Secondary Outcomes (4)

• Change in Weight

  12 weeks

• Change in peak VO2

  12 weeks

• Visceral adipose tissue area

  12 weeks

• Thigh adipose tissue area

  12 weeks

Study Arms (2)

Standard Walking

ACTIVE COMPARATOR

This arm is prescribed standard of care exercise prescription; 30 minutes of moderate intensity walking, 5 days/week.

Behavioral: Standard of Care

Interval Training

EXPERIMENTAL

This arm is prescribed body-weight based interval training 3 days per week with progressive increase in exercise intervals and sets.

Behavioral: Interval Training

Interventions

Interval Training BEHAVIORAL

Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.

Interval Training

Standard of Care BEHAVIORAL

Walking prescribed to meet current exercise guidelines; 150 minutes per week.

Standard Walking

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults 18-65 years of age
• Willing and able to provide informed consent
• Sedentary, overweight and obese adults (\<90 minutes of moderate intensity exercise)
• BMI 25≤35
• Able to safely begin an exercise program
• Have a smartphone, and willing and able to download and use the Fitbit app

You may not qualify if:

• Unable to provide informed consent.
• Known cardiovascular disease, or uncontrolled hypertension,
• Diagnosed type 1 or 2 diabetes
• Women who are pregnant or plan to become pregnant in the next 3-4 months
• Orthopedic injury/limitation or any other contraindications to exercise.
• Medications that cause weight gain (steroids, HIV-related medications, etc.), or glucose lowering medications

Sponsors & Collaborators

• Mayo Clinic: lead

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

Related Links

• Mayo Clinic Clinical Trials

MeSH Terms

Conditions

Body Weight Changes; Overweight; Obesity; Motor Activity

Interventions

High-Intensity Interval Training; Standard of Care

Condition Hierarchy (Ancestors)

Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Study Officials

• Amanda R Bonikowske

  Mayo Clinic

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Associate Consultant

Study Record Dates

• First Submitted: April 30, 2018
• First Posted: May 14, 2018
• Study Start: November 6, 2018
• Primary Completion: January 8, 2021
• Study Completion: January 8, 2021
• Last Updated: January 11, 2021

Record last verified: 2021-01

Locations

US (1)