NCT03517124

Brief Summary

This randomized clinical study aims to compare success and survival of two different ceramic tooth restoration materials. The hypothesis for the study is that fluoride treated zirconia will retain as good as lithium disilicate reinforced glass ceramic when cemented by the same resin cement. One group of patients will receive a restoration in fluoride treated zirconia, the other group will receive a restoration in reinforced glass ceramic. All restorations will be cemented in the same manner. At 3, 6, 12 and 24 months the participants will be examined.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 29, 2017

Completed
7 days until next milestone

Study Start

First participant enrolled

January 5, 2018

Completed
4 months until next milestone

First Posted

Study publicly available on registry

May 7, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

May 7, 2018

Status Verified

May 1, 2018

Enrollment Period

11 months

First QC Date

December 29, 2017

Last Update Submit

May 4, 2018

Conditions

Keywords

Zirconium oxidesurface treatmentresin cement

Outcome Measures

Primary Outcomes (2)

  • Survival

    Restoration still retained to tooth

    2 years

  • Loss of retention

    Restoration not retained to tooth

    2 years

Secondary Outcomes (4)

  • CDA-index: Romeo

    2 years

  • CDA-index: Sierra

    2 years

  • CDA-index: Tango

    2 years

  • CDA-index: Victor

    2 years

Study Arms (2)

Zirconia restorations

EXPERIMENTAL

Dental restorations in surface modified zirconia bonded to tooth substance by dual cure resin cement

Other: Ceramic tooth restoration

e.max

ACTIVE COMPARATOR

Restorations in e.max bonded to tooth substance by dual cure resin cement

Other: Ceramic tooth restoration

Interventions

Dental restorations

Zirconia restorationse.max

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older In the need of treatment on molars or premolars Lives near by Oslo

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Clinical Dentistry, University of Oslo

Oslo, 0455, Norway

Location

Related Publications (1)

  • Ruyter EI, Vajeeston N, Knarvang T, Kvam K. A novel etching technique for surface treatment of zirconia ceramics to improve adhesion of resin-based luting cements. Acta Biomater Odontol Scand. 2017 Apr 14;3(1):36-46. doi: 10.1080/23337931.2017.1309658. eCollection 2017 Jan.

    PMID: 28642930BACKGROUND

Study Officials

  • Jan Eirik Ellingsen, Professor

    Faculty of Dentistry, Institute of Clinical Dentistry

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled clinical study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

December 29, 2017

First Posted

May 7, 2018

Study Start

January 5, 2018

Primary Completion

December 1, 2018

Study Completion

December 1, 2020

Last Updated

May 7, 2018

Record last verified: 2018-05

Locations