NCT03509376

Brief Summary

This study is a randomized controlled trial comparing two ADR repair methods: nylon suturing and nylon suture with mesh enforcement. The ADR correction is performed simultaneously with abdominoplasty/ modified skin reduction abdominoplasty.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2018

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

April 11, 2018

Completed
15 days until next milestone

First Posted

Study publicly available on registry

April 26, 2018

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

April 26, 2018

Status Verified

April 1, 2018

Enrollment Period

1.8 years

First QC Date

April 11, 2018

Last Update Submit

April 25, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Low back pain

    Improvement in Oswestry 2.0 score

    At one year

Secondary Outcomes (2)

  • Recurrence

    at 1 year

  • Quality of life

    at one year

Study Arms (2)

Suture repair

EXPERIMENTAL

Diastasis recti is repaired using nylon suture for the plication

Procedure: Suture repair

Rolled mesh repair

EXPERIMENTAL

Diastasis recti is repaired with self gripping mesh to reinforce the suture line

Procedure: Rolled mesh repair

Interventions

Suture repairPROCEDURE

The diastasis is repaired with continous nylon suture

Suture repair

Continuous nylon suture is done over a narrow strip of self gripping Rolled mesh to repair the diastasis

Rolled mesh repair

Eligibility Criteria

Age18 Years - 60 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Symptomatic diastasis recti (\> 3 cm) after pregnancies, with or without a midline hernia

You may not qualify if:

  • BMI \> 28,
  • smoking
  • less than a year since the previous pregnancy or still breast feeding
  • planning further pregnancies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

HUCH Jorvi Hospital, department of Surgery

Espoo, 02480, Finland

RECRUITING

Oulu University Hospital

Oulu, Finland

RECRUITING

Related Publications (1)

  • Tuominen R, Saxen J, Jahkola T, Mikkonen J, Arokoski J, Luomajoki H, Vironen J. Rectus diastasis repair with and without mesh at 1 year: randomized clinical trial. Br J Surg. 2025 Nov 6;112(11):znaf231. doi: 10.1093/bjs/znaf231.

Study Officials

  • Tiina Jahkola

    Helsinki University Central Hospital

    PRINCIPAL INVESTIGATOR
  • Tero Rautio

    Oulu University Hospital

    PRINCIPAL INVESTIGATOR
  • Katariina Kilpivaara

    Oulu University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Reetta Tuominen

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The physiotherapist doing the clinical examinations at different phases of the study
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Patients are randomised to a suture repair or suture with mesh repair
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief surgeon

Study Record Dates

First Submitted

April 11, 2018

First Posted

April 26, 2018

Study Start

April 1, 2018

Primary Completion

December 31, 2019

Study Completion

December 31, 2021

Last Updated

April 26, 2018

Record last verified: 2018-04

Data Sharing

IPD Sharing
Will not share

Locations