Investigation of Physical Activity Level, Cardiorespiratory Fitness and Quality of Life in Patients With Asthma

NCT03509311 | Completed

• 1 other identifier: Gazi University 11
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

The primary aim of the study is to evaluate the physical activity level in patients with asthma. The secondary aims of the study are assesment of maximal and functional exercise capacity, respiratory functions, respiratory muscle strength and endurance, peripheral muscle strength, depression and anxiety levels, disease specific and respiratory quality of life, sleep and coughing associated quality of life, asthma self-management knowledge level and fatigue severity in patients with asthma.

Conditions

Asthma; Physical Activity

Keywords

Asthma; Physical activity; Cardiorespiratory fitness; Quality of life

Outcome Measures

Primary Outcomes (1)

• Physical Activity Level

  Multi sensor activity monitor

  First Day

Secondary Outcomes (14)

• Pulmonary Functions

  First Day

• Respiratory Muscle Strength

  First Day

• Respiratory Muscle Endurance

  First day

• Peripheral Muscle Strength

  First Day

• Disease Spesific Quality of Life

  First Day

Study Arms (2)

Asthma Group

That group consists from patients who had diagnosed as asthma by doctors from Chest Diseases Department of Gazi University Hospital. Physical activity level assesment, maximal and submaximal exercise capacity assesment, respiratory function assesment, respiratory muscle strength assesment, respiratory muscle endurance assesment, peripheral muscle strength assesment, quality of life assesment about disease specific, respiratory, sleep and cough associated, fatigue severity assesment, depression and anxiety level assesment and asthma management knowledge assesment apply to this group.

Healthy Group

That group consists from participants who do not have any diagnosed disease. Physical activity level assesment, maximal and submaximal exercise capacity assesment, respiratory function assesment, respiratory muscle strength assesment, respiratory muscle endurance assesment, peripheral muscle strength assesment, quality of life assesment about disease specific, respiratory, sleep and cough associated, fatigue severity assesment and depression and anxiety level assesment apply to this group.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

For Asthma Group: Thirty six patients with asthma will be included in this group For Healthy Group: Thirty six healthy volunteer will be included in this group.

You may qualify if:

• Between 18-65 years
• Diagnosed with asthma
• Receiving standard medical treatment
• Asthma Control Test score ≥ 20 point
• No smoker or ex-smoker (if ex-smoker, smoke exposure below 10 packyears)
• Willing to participate in the study

You may not qualify if:

• Have cooperation difficulty
• Have pulmonary disease (except asthma for asthma group)
• Have any cardiac, neurological or orthopedic disease that affects functional capacity
• Have pneumonia or acute infection (at last one month)
• Have been used oral corticosteroids at last one year
• Have any psychiatric diseases
• Refusing to participate
• Received or are receiving non-standard medical treatment will be excluded from study.
• Between 18-65 years without any diagnosed disease
• No smoker or ex-smoker (if ex-smoker, smoke exposure below 10 packyears)
• Willing to participate in the study will be included in healthy group.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Clinic

Ankara, 06560, Turkey (Türkiye)

Location

Related Publications (7)

• Bruno A, Uasuf CG, Insalaco G, Barazzoni R, Ballacchino A, Gjomarkaj M, Pace E. Nutritional status and physical inactivity in moderated asthmatics: A pilot study. Medicine (Baltimore). 2016 Aug;95(31):e4485. doi: 10.1097/MD.0000000000004485.

  PMID: 27495092 BACKGROUND

• Shei RJ, Paris HL, Wilhite DP, Chapman RF, Mickleborough TD. The role of inspiratory muscle training in the management of asthma and exercise-induced bronchoconstriction. Phys Sportsmed. 2016 Nov;44(4):327-334. doi: 10.1080/00913847.2016.1176546. Epub 2016 Apr 26.

  PMID: 27094568 BACKGROUND

• Ramos E, de Oliveira LV, Silva AB, Costa IP, Correa JC, Costa D, Alves VL, Donner CF, Stirbulov R, Arena R, Sampaio LM. Peripheral muscle strength and functional capacity in patients with moderate to severe asthma. Multidiscip Respir Med. 2015 Jan 21;10(1):3. doi: 10.1186/2049-6958-10-3. eCollection 2015.

  PMID: 25973197 BACKGROUND

• Vargas Becerra MH. [Physiopathology of asthma]. Rev Alerg Mex. 2009;56 Suppl 1:S24-8. Spanish.

  PMID: 20873050 BACKGROUND

• Fitting JW. [Fatigue of the respiratory muscles]. Schweiz Med Wochenschr. 1992 Feb 29;122(9):302-6. French.

  PMID: 1546280 BACKGROUND

• Cluley S, Cochrane GM. Psychological disorder in asthma is associated with poor control and poor adherence to inhaled steroids. Respir Med. 2001 Jan;95(1):37-9. doi: 10.1053/rmed.2000.0968.

  PMID: 11207015 BACKGROUND

• Stucky BD, Sherbourne CD, Edelen MO, Eberhart NK. Understanding asthma-specific quality of life: moving beyond asthma symptoms and severity. Eur Respir J. 2015 Sep;46(3):680-7. doi: 10.1183/09031936.00225014. Epub 2015 Apr 16.

  PMID: 25882804 BACKGROUND

MeSH Terms

Conditions

Asthma; Motor Activity

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Behavior

Study Officials

• Furkan Ozdemir, PT

  Gazi University

  STUDY CHAIR

• Meral Bosnak Guclu, Assoc. Prof

  Gazi University

  STUDY DIRECTOR

• Hanim Eda Goktas, PhD

  Gazi University

  PRINCIPAL INVESTIGATOR

• I. Kivilcim Oguzulgen, MD

  Gazi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof.

Study Record Dates

• First Submitted: April 17, 2018
• First Posted: April 26, 2018
• Study Start: April 20, 2018
• Primary Completion: January 30, 2019
• Study Completion: July 30, 2019
• Last Updated: June 2, 2021

Record last verified: 2021-05

Locations

TU (1)