HIIT Versus IMT on Modulating Blood Rheology in CAD Risk Factors

NCT03506984 | Unknown DMC

• 1 other identifier: Rana Elbanna
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Participants had randomly divided into two equal groups. Group (A) had received a program of high intensity interval training 30-40 minutes three times per week for one month. The participant will start cycling slowly for five minute without resistance at the beginning of the exercise as warming up, then the active phase will last 20-30 minutes, then decrease the speed with no resistance at the end of the exercise as cooling down. Group (B) will receive a program of inspiratory muscle training by using the threshold based inspiratory muscle trainer for 10-15 minute daily with frequency three times per week for four weeks.

Conditions

Coronary Artery Disease, Early-Onset

Outcome Measures

Primary Outcomes (1)

• Compare between the effect of High Intensity Interval Training versus Inspiratory Muscle Training on modulating lipid profile ( cholesterol level mg/dl, triglyceride mg/dl, LDL mg/dl and HDL mg/dl) by using the blood analyzer in CAD risk factors

  Comparison between the effect of High Intensity Interval Training versus Inspiratory Muscle Training on modulating lipid profile which composed of ( cholesterol level mg/dl, triglyceride mg/dl, LDL mg/dl and HDL mg/dl) by using the blood analyzer (Photometer, 5010, boehinger) in Coronary Artery Disease risk factors

  after 4 weeks of the trial application

Secondary Outcomes (4)

• Effect of high intensity interval training and Inspiratory Muscle Training on 6 minutes walking test by meter

  after 4 weeks of the trial application

• Compare between the effect of High Intensity Interval Training versus Inspiratory Muscle Training on modulating hematocrit value by using the blood analyzer in CAD risk factors

  after 4 weeks of the trial application

• Effect of high intensity interval training and Inspiratory Muscle Training on pulse rate (beat/min)

  after 4 weeks of the trial application

• Effect of high intensity interval training and Inspiratory Muscle Training on modified BORG scale by meter

  after 4 weeks of the trial application

Study Arms (2)

Group A

EXPERIMENTAL

the participant will do a program of inspiratory muscle training for 10-15 minutes once daily using Threshold Inspiration Muscle Training Device

Device: Threshold Inspiration Muscle Training Device

Group B

EXPERIMENTAL

the participant will start cycling slowly for five minutes without resistance at the beginning of the exercise as warming up, then the active phase will last 20-30 minutes, then decrease the speed with no resistance at the end of the exercise as cooling down using Electronic Bicycle Ergometer

Device: Electronic Bicycle Ergometer

Interventions

Threshold Inspiration Muscle Training Device DEVICE

Threshold based trainer is a small handled device.It includes a mouthpiece and a calibrated spring loaded valve. The valve control a constant inspiratory pressure training load and the patient must generate a suffient inspiratory pressure in order for the inspiratory valve to be opened and allow the air to be inhaled. The amount of resistance can be adjusted by varying the compression of the spring-loaded valve. Adjustment from 9cmH2o to 41cmH2o.

Also known as: respironics,cedarGrove,NJ 07009-1201 Made in U.S.A

Group A

Electronic Bicycle Ergometer DEVICE

Electronic Bicycle equipped with electronic break, display screen, adjustable seat, handle bar and foot straps will be used in High interval intensity training.

Also known as: Biodex LBC, made in New York

Group B

Eligibility Criteria

• Age: 45 Years - 55 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• They will be 45-55 years old participants of males.
• All of them had body mass index more than 30 kg/m2.
• All of them were diagnosed as diabetic persons for at least 5 years.
• All of them were diagnosed as a mild to moderate hypertensive persons for at least 5 years.
• All of them had a reduction in walking capacity in relation to their height, age and body mass index (BMI).

You may not qualify if:

• Unstable cardiac condition.
• Patient who were on beta blocker.
• Uncontrolled diabetes mellitus.
• Mentally unstable person.
• Patient with intermittent claudication.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Ibri hospital

Ibri, Al Dhahra, 511, Oman

RECRUITING

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Rana H Elbanna, master

  lecturer assistance at faculty of physical therapy at Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rana H Elbanna, master

CONTACT

00201120636626; rana.elbanna@yahoo.com

Sherif O Elabd, master

CONTACT

0096891107871; shiref.osama@yahoo.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: the participant
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer assistance at faculty of physical therapy at Cairo University

Model Details: Participants will randomely divided into two equal groups. Group (A) will receive a programe of high intensity interval training 30-40 minutes three times per week for one month.the participant will start cycling slowly for five minute without resistance at the beginning of the exercise as warming up, then the active phase will last 20-30 minutes, then decrease the speed with no resistance at the end of the exercise as cooling down. The participant will be closely monitored by the handheld telemetry. Group (B) will receive a program of inspiratory muscle training by using the threshold based inspiratory muscle trainer for 10-15 minutesonce daily with frequency three times per week for four weeks.

Study Record Dates

• First Submitted: March 15, 2018
• First Posted: April 24, 2018
• Study Start: September 1, 2017
• Primary Completion: April 25, 2018
• Study Completion: May 3, 2018
• Last Updated: April 24, 2018

Record last verified: 2018-04

Locations

OM (1)