NCT03499535

Brief Summary

Despite a push for tailored messages, health communications are often aimed at, and viewed by, people with varying levels of risk. This project examined-in the context of radon risk messages-whether information relevant to high-risk individuals can have an unintended influence on lower-risk individuals. Specifically, the investigators assessed whether information about lung-cancer risk from smoking reduced concerns about lung-cancer risk from radon among nonsmokers. The investigators hypothesized that non-smokers who read a message that included smoking-relevant information would express less concern about the effects of radon exposure and less interest in testing their home compared to those who read a version in which smoking-relevant information was excluded. Two studies were conducted. Although the investigators did not exclude smokers, the focus was on participants self-identifying as nonsmokers (including never smokers and former smokers).

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,390

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2015

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 7, 2015

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 22, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 22, 2016

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

March 30, 2018

Completed
18 days until next milestone

First Posted

Study publicly available on registry

April 17, 2018

Completed
Last Updated

April 19, 2019

Status Verified

April 1, 2019

Enrollment Period

9 months

First QC Date

March 30, 2018

Last Update Submit

April 17, 2019

Conditions

Keywords

Risk Perception

Outcome Measures

Primary Outcomes (2)

  • Conditional Concern Composite

    Composite formed from 4 conditional questions assessing concern, perceived impact on risk and comparative risk, and threat--if exposed to radon

    Immediately post-intervention (approx. 1 minute)

  • Interest in Testing Composite

    Composite formed from 2 questions assessing importance and intention to test home for radon

    Immediately post-intervention (approx. 2 minutes)

Secondary Outcomes (5)

  • Worry Elicited by Health Message

    Immediately post-intervention (approx. 2 minutes)

  • Likelihood Judgments about Lung Cancer

    Immediately post-intervention (approx. 4 minutes)

  • Elect to Leave Email for Raffle

    Immediately post-intervention (approx. 4 minutes)

  • Elect to Read More

    Immediately post-intervention (approx. 4 minutes)

  • Concern about Loved Ones If Exposed to Radon

    Immediately post-intervention (approx. 4 minutes)

Study Arms (7)

Study 1: Radon&Smoking Synergistic/EPA

ACTIVE COMPARATOR

Participants viewed radon and smoking risk information taken from the EPA's pamphlet on the dangers of radon gas exposure.

Behavioral: Radon & Smoking SynergisticBehavioral: EPA

Study 1: Radon&Smoking Synergistic/Idaho

ACTIVE COMPARATOR

Participants viewed radon and smoking risk information taken from Idaho's Department of Health and Human Welfare's pamphlet on the dangers of radon gas exposure.

Behavioral: Radon & Smoking SynergisticBehavioral: Idaho

Study 1: Radon Only / EPA

EXPERIMENTAL

Participants viewed only radon risk information taken from the EPA's pamphlet on the dangers of radon gas exposure.

Behavioral: Radon OnlyBehavioral: EPA

Study 1: Radon Only / Idaho

EXPERIMENTAL

Participants viewed only radon risk information taken from Idaho's Department of Health and Human Welfare's pamphlet on the dangers of radon gas exposure.

Behavioral: Radon OnlyBehavioral: Idaho

Study 2: Radon Only

EXPERIMENTAL

Participants viewed a radon-only message that focused only on the effect of radon on lung-cancer risk.

Behavioral: Radon Only

Study 2: Radon and Smoking Isolated

OTHER

Participants viewed a radon-and-smoking-isolated message that covered the individual effects of radon and of smoking on lung cancer, but without mentioning their synergistic effect.

Behavioral: Radon and Smoking Isolated

Study 2: Radon & Smoking Synergistic

ACTIVE COMPARATOR

Participants viewed a radon-and-smoking-synergistic message that covered the individual effects of radon and of smoking but that also included information about their synergistic effect.

Behavioral: Radon & Smoking Synergistic

Interventions

Participants viewed health information detailing the risks of developing lung cancer from exposure to radon gas, smoking, and their synergistic effects. This intervention represents the type of information most commonly presented in radon risk communications.

Study 1: Radon&Smoking Synergistic/EPAStudy 1: Radon&Smoking Synergistic/IdahoStudy 2: Radon & Smoking Synergistic
Radon OnlyBEHAVIORAL

Participants viewed health information detailing the risks of developing lung cancer from radon exposure. No information about the risks for developing lung cancer associated with smoking or its synergistic effect with radon exposure are included.

Study 1: Radon Only / EPAStudy 1: Radon Only / IdahoStudy 2: Radon Only

Participants viewed health information detailing the risks of developing lung cancer from radon exposure and smoking. No information describing the synergistic effects of smoking and radon exposure on lung cancer risk are included.

Study 2: Radon and Smoking Isolated
EPABEHAVIORAL

Health information modeled after the Environmental Protection Agency's (EPA) pamphlet on radon risk.

Study 1: Radon Only / EPAStudy 1: Radon&Smoking Synergistic/EPA
IdahoBEHAVIORAL

Health information modeled after the Idaho Department of Health and Human Welfare's pamphlet on radon risk.

Study 1: Radon Only / IdahoStudy 1: Radon&Smoking Synergistic/Idaho

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Live within the US
  • Have an Amazon Mechanical Turk account (website where online study was posted)

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Lung NeoplasmsSmokingRisk Reduction Behavior

Interventions

Radon

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract DiseasesBehavior

Intervention Hierarchy (Ancestors)

Elements, RadioactiveElementsInorganic ChemicalsNoble GasesGasesRadioisotopesIsotopes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participants blinded to condition.
Purpose
PREVENTION
Intervention Model
FACTORIAL
Model Details: Study 1: Participants randomly assigned to one of two conditions. Study 2: Participants randomly assigned to one of three conditions.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 30, 2018

First Posted

April 17, 2018

Study Start

August 7, 2015

Primary Completion

April 22, 2016

Study Completion

April 22, 2016

Last Updated

April 19, 2019

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will share

De-identified data and guide will be made available to other investigators upon request.

Shared Documents
ANALYTIC CODE
Time Frame
Requested data will be made available upon publication of the project.
Access Criteria
Please contact corresponding author Dr. Paul Windschitl at paul-windschitl@uiowa.edu