NCT03496909

Brief Summary

A quarter of a million women will develop breast cancer (BC) in this year alone. Many of these women will have side effects as a result of their breast cancer treatment. Radiation Fibrosis Syndrome (RFS) is a common complication from breast cancer treatment that progressively changes tissue and can cause decreased function, pain, and range of motion. The PhysioTouch is a hand held device that can be used to treat RFS and may improve the treatment of fibrotic tissue. This pilot randomized controlled trial aims to determine the efficacy of using the PhysioTouch in addition to current standard of care for treatment of BC-related RFS.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 2018

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 5, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 12, 2018

Completed
8 months until next milestone

Study Start

First participant enrolled

December 1, 2018

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2020

Completed
Last Updated

March 6, 2019

Status Verified

March 1, 2019

Enrollment Period

1.3 years

First QC Date

April 5, 2018

Last Update Submit

March 4, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in self-reported upper extremity function

    Self-reported upper extremity function as measured by QuickDash

    Baseline to 12 weeks

  • Change in self-reported pain

    Self-reported upper extremity pain as measured by the BPI

    Baseline to 12 weeks

Secondary Outcomes (2)

  • Change in affected shoulder abduction

    Baseline to 12 weeks

  • Change in affected shoulder flexion

    Baseline to 12 weeks

Study Arms (2)

Standard OT

ACTIVE COMPARATOR
Behavioral: Standard OT

PhysioTouch

EXPERIMENTAL
Behavioral: PhysioTouch

Interventions

Standard OTBEHAVIORAL

12 weekly sessions of occupational therapy tailored to patients with RFS secondary to breast cancer treatment. Sessions can include manual therapy, education, and active and passive range-of-motion, etc.

Standard OT
PhysioTouchBEHAVIORAL

12 weekly sessions of occupational therapy tailored to patients with RFS secondary to breast cancer treatment. Sessions can include use of the PhysioTouch electronic massager in lieu of manual therapy, education, and active and passive range-of-motion, etc.

PhysioTouch

Eligibility Criteria

Age21 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • History of radiation therapy for breast cancer
  • Clinical or suspected RFS
  • Reported functional impairments

You may not qualify if:

  • Metastatic disease of soft tissue
  • History of bilateral radiation therapy
  • Previously diagnosed shoulder impairments not related to RFS
  • Prior treatment with PhysioTouch
  • Current or recent pregnancy
  • Current breastfeeding
  • Other contraindications to safe and meaningful participation at discretion of study team

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Radiation Fibrosis Syndrome

Condition Hierarchy (Ancestors)

FibrosisPathologic ProcessesPathological Conditions, Signs and SymptomsRadiation InjuriesWounds and Injuries

Study Officials

  • Katie Rogers, MSOTR-CLT

    Michigan Medicine, Department of Physical Medicine & Rehabiliation

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Occupational Therapist

Study Record Dates

First Submitted

April 5, 2018

First Posted

April 12, 2018

Study Start

December 1, 2018

Primary Completion

April 1, 2020

Study Completion

April 1, 2020

Last Updated

March 6, 2019

Record last verified: 2019-03