NCT03493074

Brief Summary

This study evaluates a novel noninvasive method to dynamically monitor the effect of abdominal aortic aneurysm (AAA) and endovascular treatment of AAA (EVAR) on arterial pulse wave

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2018

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2018

Completed
19 days until next milestone

Study Start

First participant enrolled

April 8, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 10, 2018

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2021

Completed
Last Updated

October 9, 2020

Status Verified

October 1, 2020

Enrollment Period

3.4 years

First QC Date

March 20, 2018

Last Update Submit

October 8, 2020

Conditions

Outcome Measures

Primary Outcomes (2)

  • Pulse wave change from baseline during EVAR measured by a force sensor

    A force sensor node for dynamic pressure-PW measurements is utilized to detect pulse wave

    2 hours

  • Pulse wave change from baseline during EVAR measured by a optical photoplethysmographic (PPG) sensor

    Optical photoplethysmographic (PPG) sensor node is used for volume pulse measurements

    2 hours

Secondary Outcomes (4)

  • Pulse wave change from baseline after EVAR measured by a force sensor

    30 days

  • Pulse wave change from baseline after EVAR measured by a optical photoplethysmographic (PPG) sensor

    30 days

  • Pulse wave change from baseline after EVAR measured by a force sensor

    12 months

  • Pulse wave change from baseline after EVAR measured by a optical

    12 months

Interventions

The sensors are noninvasively attached

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Finnish, Caucasian

You may qualify if:

  • The patient has been clinically examined at policlinic of vascular surgery
  • The patient has been examined with computed tomography (CT) imaging
  • The patient has been considered a candidate for the EVAR of the AAA

You may not qualify if:

  • A patient has a pacemaker
  • A medical doctor decides that the measurement disturbs or risks the subject's treatment process
  • Subject's denial (or withdrawal)
  • A patient has at least one amputated limb
  • The age of the test subject candidate is less than 18 years
  • A test subject candidate is not able to understand the study or is not legally competent
  • A test subject candidate has Ehlers-Danlos syndrome or Marfan syndrome

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tampere University Hospital

Tampere, FI-33014, Finland

RECRUITING

MeSH Terms

Conditions

Cardiovascular DiseasesAortic Aneurysm, Abdominal

Condition Hierarchy (Ancestors)

Aortic AneurysmAneurysmVascular DiseasesAortic Diseases

Central Study Contacts

Niku Oksala, Professor

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2018

First Posted

April 10, 2018

Study Start

April 8, 2018

Primary Completion

August 30, 2021

Study Completion

August 30, 2021

Last Updated

October 9, 2020

Record last verified: 2020-10

Locations