Predictive Factors of Unpredicted Movement in Motor Evoked Potential

NCT03489785 | Unknown

• 1 other identifier: B-1801-444-102
• Study Type: observational
• Target: 850
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to identify the predictive factors of unpredicted movement in motor evoked potential (MEP) during intraoperative neurophysiologic monitoring in adult patients undergoing brain surgery.

Conditions

Involuntary Movements; Brain Surgery

Keywords

Predicted factor; Motor Evoked Potentials

Outcome Measures

Primary Outcomes (1)

• Predictive factors of unpredicted movement

  The investigators retrospectively compare the data of patients with and without unpredictable and unacceptable movement during surgery. For continuous variables, values were compared using the independent t-test. Differences in proportions were compared using chi-square test. Variables with P-values \< 0.05 in the primary test were selected and univariate binary logistic regression analyses were conducted to identify the factors predictive of an unpredictable and unacceptable movement. P-value \< 0.05 was considered statistically significant.

  during brain surgery

Study Arms (2)

Movement

If there is unexpected movement

No movement

If there is no unexpected movement

Eligibility Criteria

• Age: 19 Years - 74 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

From June 2003 to August 2017, patients who underwent motor-evoked potential monitoring during brain surgery under partial neuromuscular relaxation at the Seoul National University Bundang Hospital were included in this study.

You may qualify if:

• From June 2003 to August 2017, patients who underwent motor-evoked potential monitoring during brain surgery under partial neuromuscular relaxation at the Seoul National University Bundang Hospital.

You may not qualify if:

• Age : 18 or younger and 75 or older
• Anesthesiologists physical status classes III or more
• body mass index(BMI) \< 18.5 kg/m\^2 or BMI \> 25 kg/m\^2
• Patients who received medications that affect muscle relaxation recovery other than anticonvulsants
• OT/PT \> 40 IU/L, Cr \> 1.4 mg/dl
• Moderate to severe respiratory or heart disease

Sponsors & Collaborators

• Seoul National University Hospital: lead

Study Sites (1)

Seoul National University Bundang Hospital

Seongnam-si, Bundang-gu, South Korea

RECRUITING

MeSH Terms

Conditions

Dyskinesias

Condition Hierarchy (Ancestors)

Movement Disorders; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Soowon Lee

CONTACT

82-10-4711-5380; superiorvii@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2018
• First Posted: April 5, 2018
• Study Start: June 1, 2003
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2018
• Last Updated: April 30, 2018

Record last verified: 2018-01

Locations

KR (1)